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kinase

American  
[kahy-neys, -neyz,kin-eys, -eyz]/ ˈkaɪ neɪs, -neɪz, ˈkɪn eɪs, -eɪz /

noun

Biochemistry.
  1. a transferase that catalyzes the phosphorylation of a substrate by ATP.


kinase British  
/ ˈkɪn-, ˈkaɪneɪz /

noun

  1. any enzyme that can convert an inactive zymogen to the corresponding enzyme

  2. any enzyme that brings about the phosphorylation of a molecule

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

kinase Scientific  
/ kīnās′,-nāz′,kĭnās′,-āz′ /
  1. Any of various enzymes that catalyze the transfer of a phosphate group from a donor, such as ADP or ATP, to an acceptor.


Etymology

Origin of kinase

First recorded in 1900–05;kin(etic) +-ase

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

One of these proteins is dual leucine zipper kinase, or DLK, which acts as a sensor for neuronal damage and becomes active when metabolism is disrupted.

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By demonstrating that CENP-E regulates the earliest attachments and by connecting this regulation to Aurora kinase activity, the Zagreb team linked two processes previously thought to act separately.

FromScience Daily

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The protein ZAK -- a so-called kinase, that is, an enzyme which activates other molecules by transferring a phosphate group to them -- plays a central role in controlling this stress response.

FromScience Daily

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The researchers found that betaine binds to and blocks TBK1, a kinase that drives inflammation.

FromScience Daily

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PKA consists of a catalytic subunit responsible for kinase activity and a regulatory subunit that inhibits enzyme activity.

FromScience Daily

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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.


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