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Paneth's cell
Paneth's cellPaneth's cells (highly magnified).

Paneth’s cell

anatomy
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Also known as: Davidoff’s cell, cells of Paneth
Also called:
Davidoff’s Cell
Related Topics:
cell

Paneth’s cell, specialized type of epithelialcell found in the mucous-membrane lining of thesmall intestine and of theappendix, at the base of tubelike depressions known as Lieberkühn glands. Named for the 19th-century Austrian physiologist Joseph Paneth, the cell has onenucleus at its base and densely packed secretory granules throughout the rest of its body. The cells’ function is not totally known, nor is their manner ofdischarging their granules. They are known to secrete large amounts of protein-rich material and are thought to secrete the enzyme peptidase, which breaks peptide molecules into amino acids suitable for assimilation by the body. In humans the granules are found to contain carbohydrates, proteins, and radioactive zinc. In mice a specific protein,lysozyme, known to destroy somebacteria, is believed to be present in the granules. This suggests that the Paneth cell might also have an antibacterial function.

This article was most recently revised and updated byAmy Tikkanen.

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