Saint-Lô, town, capital of Manchedépartement,Normandyrégion, northwesternFrance. It lies on a promontory dominating the Vire River valley. Called Briovera in Gallo-Roman times, it was renamed for Saint Lô, the 6th-century bishop ofCoutances. In the Middle Ages it was a major fortress and was noted for its weaving. In 1796 Saint-Lô replaced Coutances as capital of Manchedépartement. The town, a vital communications centre because of its location at a major crossroads, was almost destroyed inWorld War II after the Allied landings in June 1944, being taken by U.S. forces on July 18. Its reconstruction, begun in 1948, included restoration ofmedieval ramparts (revealed by the bombardment) overlooking the river valley. The Gothic-style church of Notre-Dame (14th–17th century) has also been restored.

Saint-Lô is a market town and administrative centre with some light industry, including the processing of local agricultural output. It is surrounded by farms that specialize in the breeding ofThoroughbred race horses. Pop. (1999) 20,090; (2014 est.) 19,426.