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Bioconductor 3.22 Released

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topdownr

This is thereleased version of topdownr; for the devel version, seetopdownr.

Investigation of Fragmentation Conditions in Top-Down Proteomics

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DOI: 10.18129/B9.bioc.topdownr


Bioconductor version: Release (3.22)

The topdownr package allows automatic and systemic investigation of fragment conditions. It creates Thermo Orbitrap Fusion Lumos method files to test hundreds of fragmentation conditions. Additionally it provides functions to analyse and process the generated MS data and determine the best conditions to maximise overall fragment coverage.

Author: Sebastian Gibb [aut, cre]ORCID iD ORCID: 0000-0001-7406-4443, Pavel Shliaha [aut]ORCID iD ORCID: 0000-0003-3092-0724, Ole Nørregaard Jensen [aut]ORCID iD ORCID: 0000-0003-1862-8528

Maintainer: Sebastian Gibb <mail at sebastiangibb.de>

Citation (from within R, entercitation("topdownr")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("topdownr")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("topdownr")
Data Generation for topdownrHTMLR Script
Fragmentation Analysis with topdownrHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsCoverage,ImmunoOncology,Infrastructure,MassSpectrometry,Proteomics,Software
Version1.32.0
In Bioconductor sinceBioC 3.6 (R-3.4) (8 years)
LicenseGPL (>= 3)
DependsR (>= 3.5), methods,BiocGenerics(>= 0.20.0),ProtGenerics(>= 1.10.0),Biostrings(>= 2.42.1),S4Vectors(>= 0.12.2)
ImportsgrDevices, stats, tools, utils,Biobase,Matrix (>= 1.4-2),MSnbase(>= 2.33.5),PSMatch(>= 1.11.4),ggplot2 (>= 2.2.1),mzR(>= 2.27.5)
System Requirements
URLhttps://codeberg.org/sgibb/topdownr/
Bug Reportshttps://codeberg.org/sgibb/topdownr/issues/
See More
Suggeststopdownrdata(>= 0.2),knitr,rmarkdown,ranger,testthat,BiocStyle,xml2
Linking To
Enhances
Depends On Metopdownrdata
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source Packagetopdownr_1.32.0.tar.gz
Windows Binary (x86_64) topdownr_1.32.0.zip
macOS Binary (x86_64)topdownr_1.32.0.tgz
macOS Binary (arm64)topdownr_1.32.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/topdownr
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/topdownr
Bioc Package Browserhttps://code.bioconductor.org/browse/topdownr/
Package Short Urlhttps://bioconductor.org/packages/topdownr/
Package Downloads ReportDownload Stats

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