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signeR

This is thereleased version of signeR; for the devel version, seesigneR.

Empirical Bayesian approach to mutational signature discovery

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DOI: 10.18129/B9.bioc.signeR


Bioconductor version: Release (3.22)

The signeR package provides an empirical Bayesian approach to mutational signature discovery. It is designed to analyze single nucleotide variation (SNV) counts in cancer genomes, but can also be applied to other features as well. Functionalities to characterize signatures or genome samples according to exposure patterns are also provided.

Author: Rafael Rosales, Rodrigo Drummond, Renan Valieris, Alexandre Defelicibus, Israel Tojal da Silva

Maintainer: Renan Valieris <renan.valieris at accamargo.org.br>

Citation (from within R, entercitation("signeR")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("signeR")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("signeR")
signeRHTMLR Script
signeRFlowHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsGenomicVariation,Software,SomaticMutation,StatisticalMethod,Visualization
Version2.12.0
In Bioconductor sinceBioC 3.4 (R-3.3) (9 years)
LicenseGPL-3
DependsR (>= 4.1.0),NMF
ImportsBiocGenerics,Biostrings,class, grDevices,GenomeInfoDb,GenomicRanges,IRanges,nloptr, methods, stats, utils,PMCMRplus, parallel,pvclust,ppclust,clue,survival,maxstat,future,VGAM,MASS,kknn,glmnet,e1071,randomForest,ada,future.apply,ggplot2,pROC,pheatmap,RColorBrewer,listenv,reshape2,scales,survminer,dplyr,ggpubr,cowplot,tibble,readr,shiny,shinydashboard,shinycssloaders,shinyWidgets,bsplus,DT,magrittr,tidyr,BiocFileCache,proxy,rtracklayer,BSgenome,broom,VariantAnnotation
System RequirementsC++14
URLhttps://github.com/TojalLab/signeR
See More
Suggestsknitr,BSgenome.Hsapiens.UCSC.hg19,BSgenome.Hsapiens.UCSC.hg38,rmarkdown
Linking ToRcpp,RcppArmadillo (>= 0.7.100)
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackagesigneR_2.12.0.tar.gz
Windows Binary (x86_64) signeR_2.12.0.zip
macOS Binary (x86_64)signeR_2.12.0.tgz
macOS Binary (arm64)signeR_2.12.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/signeR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/signeR
Bioc Package Browserhttps://code.bioconductor.org/browse/signeR/
Package Short Urlhttps://bioconductor.org/packages/signeR/
Package Downloads ReportDownload Stats

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