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scDiagnostics

This is thereleased version of scDiagnostics; for the devel version, seescDiagnostics.

Cell type annotation diagnostics

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DOI: 10.18129/B9.bioc.scDiagnostics


Bioconductor version: Release (3.22)

The scDiagnostics package provides diagnostic plots to assess the quality of cell type assignments from single cell gene expression profiles. The implemented functionality allows to assess the reliability of cell type annotations, investigate gene expression patterns, and explore relationships between different cell types in query and reference datasets allowing users to detect potential misalignments between reference and query datasets. The package also provides visualization capabilities for diagnostics purposes.

Author: Anthony Christidis [aut, cre]ORCID iD ORCID: 0000-0002-4565-6279, Andrew Ghazi [aut], Smriti Chawla [aut], Nitesh Turaga [ctb], Ludwig Geistlinger [aut], Robert Gentleman [aut]

Maintainer: Anthony Christidis <anthony-alexander_christidis at hms.harvard.edu>

Citation (from within R, entercitation("scDiagnostics")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("scDiagnostics")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("scDiagnostics")
1. Getting Started with scDiagnosticsHTMLR Script
2. Visualization of Cell Type AnnotationsHTMLR Script
3. Evaluation of Dataset and Marker Gene AlignmentHTMLR Script
4. Detection and Analysis of Annotation AnomaliesHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsAnnotation,Classification,Clustering,GeneExpression,RNASeq,SingleCell,Software,Transcriptomics
Version1.4.0
In Bioconductor sinceBioC 3.20 (R-4.4) (1 year)
LicenseArtistic-2.0
DependsR (>= 4.4.0)
ImportsSingleCellExperiment, methods,isotree,FNN,igraph,ggplot2,GGally,ggridges,SummarizedExperiment,ranger,transport,cramer,rlang,bluster,scales,MASS,stringr,Matrix, grDevices
System Requirements
URLhttps://github.com/ccb-hms/scDiagnostics
Bug Reportshttps://github.com/ccb-hms/scDiagnostics/issues
See More
SuggestsAUCell,BiocStyle,knitr,rmarkdown,scran,scRNAseq,SingleR,celldex,scuttle,scater,dplyr,ComplexHeatmap, grid,testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackagescDiagnostics_1.4.0.tar.gz
Windows Binary (x86_64) scDiagnostics_1.4.0.zip
macOS Binary (x86_64)scDiagnostics_1.4.0.tgz
macOS Binary (arm64)scDiagnostics_1.4.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/scDiagnostics
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/scDiagnostics
Bioc Package Browserhttps://code.bioconductor.org/browse/scDiagnostics/
Package Short Urlhttps://bioconductor.org/packages/scDiagnostics/
Package Downloads ReportDownload Stats

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