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pathMED

This is thereleased version of pathMED; for the devel version, seepathMED.

Scoring Personalized Molecular Portraits

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DOI: 10.18129/B9.bioc.pathMED


Bioconductor version: Release (3.22)

PathMED is a collection of tools to facilitate precision medicine studies with omics data (e.g. transcriptomics). Among its funcionalities, genesets scores for individual samples may be calculated with several methods. These scores may be used to train machine learning models and to predict clinical features on new data. For this, several machine learning methods are evaluated in order to select the best method based on internal validation and to tune the hyperparameters. Performance metrics and a ready-to-use model to predict the outcomes for new patients are returned.

Author: Jordi Martorell-Marugán [cre, aut]ORCID iD ORCID: 0000-0002-5186-0735, Daniel Toro-Domínguez [aut]ORCID iD ORCID: 0000-0001-8440-312X, Raúl López-Domínguez [aut]ORCID iD ORCID: 0000-0001-8634-117X, Iván Ellson [aut]ORCID iD ORCID: 0000-0001-6307-3141

Maintainer: Jordi Martorell-Marugán <jmartorellm at gmail.com>

Citation (from within R, entercitation("pathMED")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("pathMED")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("pathMED")
pathMEDHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsClassification,FeatureExtraction,Pathways,Software,Transcriptomics
Version1.2.0
In Bioconductor sinceBioC 3.21 (R-4.5) (0.5 years)
LicenseGPL-2
DependsR (>= 4.5.0)
ImportsBiocParallel,caret,caretEnsemble,decoupleR,ggplot2,GSVA,factoextra,FactoMineR,magrittr,matrixStats, methods,metrica,pbapply,reshape2,singscore, stats,stringi,dplyr
System Requirements
URLhttps://github.com/jordimartorell/pathMED
Bug Reportshttps://github.com/jordimartorell/pathMED/issues
See More
Suggestsada,AUCell,Biobase,BiocGenerics,BiocStyle,fgsea(>= 1.15.4),gam,GSEABase,import,kernlab,klaR,knitr,mboost,MLeval,randomForest,ranger,rmarkdown,RUnit,SummarizedExperiment, utils,xgboost
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Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackagepathMED_1.2.0.tar.gz
Windows Binary (x86_64) pathMED_1.2.0.zip
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/pathMED
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/pathMED
Bioc Package Browserhttps://code.bioconductor.org/browse/pathMED/
Package Short Urlhttps://bioconductor.org/packages/pathMED/
Package Downloads ReportDownload Stats

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