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methylclock

This is thereleased version of methylclock; for the devel version, seemethylclock.

Methylclock - DNA methylation-based clocks

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DOI: 10.18129/B9.bioc.methylclock


Bioconductor version: Release (3.22)

This package allows to estimate chronological and gestational DNA methylation (DNAm) age as well as biological age using different methylation clocks. Chronological DNAm age (in years) : Horvath's clock, Hannum's clock, BNN, Horvath's skin+blood clock, PedBE clock and Wu's clock. Gestational DNAm age : Knight's clock, Bohlin's clock, Mayne's clock and Lee's clocks. Biological DNAm clocks : Levine's clock and Telomere Length's clock.

Author: Dolors Pelegri-Siso [aut, cre]ORCID iD ORCID: 0000-0002-5993-3003, Juan R. Gonzalez [aut]ORCID iD ORCID: 0000-0003-3267-2146

Maintainer: Dolors Pelegri-Siso <dolors.pelegri at isglobal.org>

Citation (from within R, entercitation("methylclock")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("methylclock")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("methylclock")
DNAm age using diffrent methylation clocksHTMLR Script
Reference ManualPDF
NEWSText
LICENSEText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsBiologicalQuestion,DNAMethylation,Normalization,Preprocessing,Software,StatisticalMethod
Version1.16.0
In Bioconductor sinceBioC 3.14 (R-4.1) (4 years)
LicenseMIT + fileLICENSE
DependsR (>= 4.1.0),methylclockData,devtools,quadprog
ImportsRcpp (>= 1.0.6),ExperimentHub,dplyr,impute,PerformanceAnalytics,Biobase,ggpmisc,tidyverse,ggplot2,ggpubr,minfi,tibble,RPMM, stats, graphics,tidyr,gridExtra,preprocessCore,dynamicTreeCut,planet
System Requirements
URLhttps://github.com/isglobal-brge/methylclock
Bug Reportshttps://github.com/isglobal-brge/methylclock/issues
See More
SuggestsBiocStyle,knitr,GEOquery,rmarkdown
Linking ToRcpp
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source Packagemethylclock_1.16.0.tar.gz
Windows Binary (x86_64) methylclock_1.16.0.zip
macOS Binary (x86_64)methylclock_1.16.0.tgz
macOS Binary (arm64)methylclock_1.16.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/methylclock
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/methylclock
Bioc Package Browserhttps://code.bioconductor.org/browse/methylclock/
Package Short Urlhttps://bioconductor.org/packages/methylclock/
Package Downloads ReportDownload Stats

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