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linkSet

This is thereleased version of linkSet; for the devel version, seelinkSet.

Base Classes for Storing Genomic Link Data

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DOI: 10.18129/B9.bioc.linkSet


Bioconductor version: Release (3.22)

Provides a comprehensive framework for representing, analyzing, and visualizing genomic interactions, particularly focusing on gene-enhancer relationships. The package extends the GenomicRanges infrastructure to handle paired genomic regions with specialized methods for chromatin interaction data from Hi-C, Promoter Capture Hi-C (PCHi-C), and single-cell ATAC-seq experiments. Key features include conversion from common interaction formats, annotation of promoters and enhancers, distance-based analyses, interaction strength metrics, statistical modeling using CHiCANE methodology, and tailored visualization tools. The package aims to standardize the representation of genomic interaction data while providing domain-specific functions not available in general genomic interaction packages.

Author: Gilbert Han [aut, cre]ORCID iD ORCID: 0009-0000-0293-2467

Maintainer: Gilbert Han <GilbertHan1011 at gmail.com>

Citation (from within R, entercitation("linkSet")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("linkSet")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("linkSet")
Hi-C Workflow with linkSetHTMLR Script
linkSet: Base Classes for Storing Genomic Link DataHTMLR Script
Reference ManualPDF
NEWSText
LICENSEText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsCoverage,DataRepresentation,HiC,Sequencing,SingleCell,Software
Version1.0.0
In Bioconductor sinceBioC 3.22 (R-4.5) (< 6 months)
LicenseMIT + fileLICENSE
DependsGenomicRanges,S4Vectors, R (>= 4.5.0)
Importsmethods,IRanges,GenomeInfoDb,BiocGenerics,Organism.dplyr,InteractionSet,ggplot2,patchwork,scales,foreach,iterators, stats,rlang,MASS,data.table,DBI,doParallel,AnnotationDbi
System Requirements
URLhttps://github.com/GilbertHan1011/linkSethttps://gilberthan1011.github.io/linkSet
Bug Reportshttps://github.com/GilbertHan1011/linkSet/issues/new
See More
Suggestsknitr,rmarkdown,testthat,TxDb.Mmusculus.UCSC.mm10.knownGene,TxDb.Hsapiens.UCSC.hg38.knownGene,TxDb.Hsapiens.UCSC.hg19.knownGene,org.Mm.eg.db,org.Hs.eg.db,GenomicFeatures,GenomicInteractions,gamlss,gamlss.tr,BiocStyle,rtracklayer
Linking To
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Depends On Me
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Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackagelinkSet_1.0.0.tar.gz
Windows Binary (x86_64) linkSet_1.0.0.zip
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/linkSet
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/linkSet
Bioc Package Browserhttps://code.bioconductor.org/browse/linkSet/
Package Short Urlhttps://bioconductor.org/packages/linkSet/
Package Downloads ReportDownload Stats

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