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lefser

This is thereleased version of lefser; for the devel version, seelefser.

R implementation of the LEfSE method for microbiome biomarker discovery

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DOI: 10.18129/B9.bioc.lefser


Bioconductor version: Release (3.22)

lefser is the R implementation of the popular microbiome biomarker discovery too, LEfSe. It uses the Kruskal-Wallis test, Wilcoxon-Rank Sum test, and Linear Discriminant Analysis to find biomarkers from two-level classes (and optional sub-classes).

Author: Sehyun Oh [cre, ctb]ORCID iD ORCID: 0000-0002-9490-3061, Asya Khleborodova [aut], Samuel Gamboa-Tuz [ctb], Marcel Ramos [ctb]ORCID iD ORCID: 0000-0002-3242-0582, Ludwig Geistlinger [ctb]ORCID iD ORCID: 0000-0002-2495-5464, Levi Waldron [ctb]ORCID iD ORCID: 0000-0003-2725-0694

Maintainer: Sehyun Oh <shbrief at gmail.com>

Citation (from within R, entercitation("lefser")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("lefser")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("lefser")
QuickstartHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsClassification,DifferentialExpression,Microbiome,Sequencing,Software,StatisticalMethod
Version1.20.2
In Bioconductor sinceBioC 3.12 (R-4.0) (5 years)
LicenseArtistic-2.0
DependsSummarizedExperiment, R (>= 4.5.0)
Importscoin,MASS,ggplot2,S4Vectors, stats, methods, utils,dplyr,testthat,tibble,tidyr,forcats,stringr,ggtree,BiocGenerics,ape,ggrepel,mia,purrr,tidyselect,treeio
System Requirements
URLhttps://github.com/waldronlab/lefser
Bug Reportshttps://github.com/waldronlab/lefser/issues
See More
Suggestsknitr,rmarkdown,curatedMetagenomicData,BiocStyle,phyloseq,pkgdown,covr,withr
Linking To
Enhances
Depends On Me
Imports Me
Suggests Medar,curatedMetagenomicData,ggpicrust2
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source Packagelefser_1.20.2.tar.gz
Windows Binary (x86_64) lefser_1.20.2.zip
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/lefser
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/lefser
Bioc Package Browserhttps://code.bioconductor.org/browse/lefser/
Package Short Urlhttps://bioconductor.org/packages/lefser/
Package Downloads ReportDownload Stats
Old Source Packages for BioC 3.22Source Archive

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