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knowYourCG
This is thereleased version of knowYourCG; for the devel version, seeknowYourCG.
Functional analysis of DNA methylome datasets
Bioconductor version: Release (3.22)
KnowYourCG (KYCG) is a supervised learning framework designed for the functional analysis of DNA methylation data. Unlike existing tools that focus on genes or genomic intervals, KnowYourCG directly targets CpG dinucleotides, featuring automated supervised screenings of diverse biological and technical influences, including sequence motifs, transcription factor binding, histone modifications, replication timing, cell-type-specific methylation, and trait-epigenome associations. KnowYourCG addresses the challenges of data sparsity in various methylation datasets, including low-pass Nanopore sequencing, single-cell DNA methylomes, 5-hydroxymethylation profiles, spatial DNA methylation maps, and array-based datasets for epigenome-wide association studies and epigenetic clocks.
Author: Zhou Wanding [aut]
ORCID: 0000-0001-9126-1932, Goldberg David [aut, cre] ORCID: 0000-0002-9622-4708, Fu Hongxiang [ctb]
Maintainer: Goldberg David <golddc72 at pennmedicine.upenn.edu>
citation("knowYourCG")):Installation
To install this package, start R (version "4.5") and enter:
if (!require("BiocManager", quietly = TRUE)) install.packages("BiocManager")BiocManager::install("knowYourCG")For older versions of R, please refer to the appropriateBioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("knowYourCG")| 1. Sequencing Data Analysis | HTML | R Script |
| 2. Array Data Analysis | HTML | R Script |
| 3. Continuous Variable Enrichment Analysis | HTML | R Script |
| Reference Manual | ||
| NEWS | Text | |
| LICENSE | Text |
Details
| biocViews | DNAMethylation,Epigenetics,MethylationArray,Sequencing,SingleCell,Software,Spatial |
| Version | 1.6.0 |
| In Bioconductor since | BioC 3.19 (R-4.4) (1.5 years) |
| License | MIT + fileLICENSE |
| Depends | R (>= 4.4.0) |
| Imports | sesameData,dplyr, methods,rlang,GenomicRanges,IRanges,reshape2,S4Vectors, stats,stringr, utils,ggplot2,ggrepel,tibble,wheatmap,magrittr |
| System Requirements | |
| URL | https://github.com/zhou-lab/knowYourCG |
| Bug Reports | https://github.com/zhou-lab/knowYourCG/issues |
See More
| Suggests | testthat (>= 3.0.0),SummarizedExperiment,rmarkdown,knitr,sesame,gprofiler2,ggrastr |
| Linking To | |
| Enhances | |
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report | Build Report |
Package Archives
FollowInstallation instructions to use this package in your R session.
| Source Package | knowYourCG_1.6.0.tar.gz |
| Windows Binary (x86_64) | knowYourCG_1.5.2.zip |
| macOS Binary (x86_64) | knowYourCG_1.6.0.tgz |
| macOS Binary (arm64) | knowYourCG_1.6.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/knowYourCG |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/knowYourCG |
| Bioc Package Browser | https://code.bioconductor.org/browse/knowYourCG/ |
| Package Short Url | https://bioconductor.org/packages/knowYourCG/ |
| Package Downloads Report | Download Stats |