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cleanUpdTSeq

This is thereleased version of cleanUpdTSeq; for the devel version, seecleanUpdTSeq.

cleanUpdTSeq cleans up artifacts from polyadenylation sites from oligo(dT)-mediated 3' end RNA sequending data

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DOI: 10.18129/B9.bioc.cleanUpdTSeq


Bioconductor version: Release (3.22)

This package implements a Naive Bayes classifier for accurately differentiating true polyadenylation sites (pA sites) from oligo(dT)-mediated 3' end sequencing such as PAS-Seq, PolyA-Seq and RNA-Seq by filtering out false polyadenylation sites, mainly due to oligo(dT)-mediated internal priming during reverse transcription. The classifer is highly accurate and outperforms other heuristic methods.

Author: Sarah Sheppard, Haibo Liu, Jianhong Ou, Nathan Lawson, Lihua Julie Zhu

Maintainer: Jianhong Ou <jou at morgridge.org>; Lihua Julie Zhu <Julie.Zhu at umassmed.edu>

Citation (from within R, entercitation("cleanUpdTSeq")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("cleanUpdTSeq")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("cleanUpdTSeq")
cleanUpdTSeq VignetteHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViews3' end sequencing,Sequencing,Software,internal priming,polyadenylation site
Version1.48.0
In Bioconductor sinceBioC 2.13 (R-3.0) (12 years)
LicenseGPL-2
DependsR (>= 3.5.0),BSgenome.Drerio.UCSC.danRer7, methods
ImportsBSgenome,GenomicRanges,seqinr,e1071,Biostrings,Seqinfo,IRanges, utils,stringr, stats,S4Vectors
System Requirements
URL
See More
SuggestsBiocStyle,rmarkdown,knitr,RUnit,BiocGenerics(>= 0.1.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackagecleanUpdTSeq_1.48.0.tar.gz
Windows Binary (x86_64) cleanUpdTSeq_1.48.0.zip
macOS Binary (x86_64)cleanUpdTSeq_1.48.0.tgz
macOS Binary (arm64)cleanUpdTSeq_1.48.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/cleanUpdTSeq
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/cleanUpdTSeq
Bioc Package Browserhttps://code.bioconductor.org/browse/cleanUpdTSeq/
Package Short Urlhttps://bioconductor.org/packages/cleanUpdTSeq/
Package Downloads ReportDownload Stats

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