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cfDNAPro

This is thereleased version of cfDNAPro; for the devel version, seecfDNAPro.

cfDNAPro extracts and Visualises biological features from whole genome sequencing data of cell-free DNA

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DOI: 10.18129/B9.bioc.cfDNAPro


Bioconductor version: Release (3.22)

cfDNA fragments carry important features for building cancer sample classification ML models, such as fragment size, and fragment end motif etc. Analyzing and visualizing fragment size metrics, as well as other biological features in a curated, standardized, scalable, well-documented, and reproducible way might be time intensive. This package intends to resolve these problems and simplify the process. It offers two sets of functions for cfDNA feature characterization and visualization.

Author: Haichao Wang [aut, cre], Hui Zhao [ctb], Elkie Chan [ctb], Christopher Smith [ctb], Tomer Kaplan [ctb], Florian Markowetz [ctb], Nitzan Rosenfeld [ctb]

Maintainer: Haichao Wang <hw538 at cam.ac.uk>

Citation (from within R, entercitation("cfDNAPro")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("cfDNAPro")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("cfDNAPro")
cfDNAPro TutorialHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsSequencing,Software,Visualization,WholeGenome
Version1.16.0
In Bioconductor sinceBioC 3.12 (R-4.0) (5 years)
LicenseGPL-3
DependsR (>= 4.1.0),magrittr (>= 1.5.0)
Importstibble,GenomicAlignments,IRanges,plyranges,GenomeInfoDb,GenomicRanges,BiocGenerics, stats, utils,dplyr (>= 0.8.3),stringr (>= 1.4.0),quantmod (>= 0.4),ggplot2 (>= 3.2.1),Rsamtools(>= 2.4.0),rlang (>= 0.4.0),BSgenome.Hsapiens.UCSC.hg38,BSgenome.Hsapiens.UCSC.hg19,BSgenome.Hsapiens.NCBI.GRCh38
System Requirements
URLhttps://github.com/hw538/cfDNAPro
See More
Suggestsscales,ggpubr,knitr (>= 1.23),rmarkdown (>= 1.14),devtools (>= 2.3.0),BiocStyle,testthat
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Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackagecfDNAPro_1.16.0.tar.gz
Windows Binary (x86_64) cfDNAPro_1.16.0.zip
macOS Binary (x86_64)cfDNAPro_1.16.0.tgz
macOS Binary (arm64)cfDNAPro_1.16.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/cfDNAPro
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/cfDNAPro
Bioc Package Browserhttps://code.bioconductor.org/browse/cfDNAPro/
Package Short Urlhttps://bioconductor.org/packages/cfDNAPro/
Package Downloads ReportDownload Stats

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