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barbieQ

This is thereleased version of barbieQ; for the devel version, seebarbieQ.

Analyze Barcode Data from Clonal Tracking Experiments

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DOI: 10.18129/B9.bioc.barbieQ


Bioconductor version: Release (3.22)

The barbieQ package provides a series of robust statistical tools for analysing barcode count data generated from cell clonal tracking (i.e., lineage tracing) experiments. In these experiments, an initial cell and its offspring collectively form a clone (i.e., lineage). A unique barcode sequence, incorporated into the DNA of the inital cell, is inherited within the clone. This one-to-one mapping of barcodes to clones enables clonal tracking of their behaviors. By counting barcodes, researchers can quantify the population abundance of individual clones under specific experimental perturbations. barbieQ supports barcode count data preprocessing, statistical testing, and visualization.

Author: Liyang Fei [aut, cre]ORCID iD ORCID: 0000-0002-3293-2094

Maintainer: Liyang Fei <liyang.fei at petermac.org>

Citation (from within R, entercitation("barbieQ")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("barbieQ")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("barbieQ")
Quick start to barbieQHTMLR Script
Reference ManualPDF
NEWSText
LICENSEText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsPreprocessing,Regression,Sequencing,Software,Visualization
Version1.2.0
In Bioconductor sinceBioC 3.21 (R-4.5) (0.5 years)
LicenseGPL-3
DependsR (>= 4.5)
Importsmagrittr,tidyr,dplyr, grid,circlize,ComplexHeatmap,ggplot2,logistf,limma, stats,igraph, utils,data.table,S4Vectors,SummarizedExperiment
System Requirements
URLhttps://github.com/Oshlack/barbieQ/issues
Bug Reportshttps://github.com/Oshlack/barbieQ
See More
Suggestsknitr,rmarkdown,testthat (>= 3.0.0),BiocStyle
Linking To
Enhances
Depends On Me
Imports Me
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Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackagebarbieQ_1.2.0.tar.gz
Windows Binary (x86_64) barbieQ_1.2.0.zip (64-bit only)
macOS Binary (x86_64)barbieQ_1.2.0.tgz
macOS Binary (arm64)barbieQ_1.2.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/barbieQ
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/barbieQ
Bioc Package Browserhttps://code.bioconductor.org/browse/barbieQ/
Package Short Urlhttps://bioconductor.org/packages/barbieQ/
Package Downloads ReportDownload Stats

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