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airpart

This is thereleased version of airpart; for the devel version, seeairpart.

Differential cell-type-specific allelic imbalance

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DOI: 10.18129/B9.bioc.airpart


Bioconductor version: Release (3.22)

Airpart identifies sets of genes displaying differential cell-type-specific allelic imbalance across cell types or states, utilizing single-cell allelic counts. It makes use of a generalized fused lasso with binomial observations of allelic counts to partition cell types by their allelic imbalance. Alternatively, a nonparametric method for partitioning cell types is offered. The package includes a number of visualizations and quality control functions for examining single cell allelic imbalance datasets.

Author: Wancen Mu [aut, cre]ORCID iD ORCID: 0000-0002-5061-7581, Michael Love [aut, ctb]ORCID iD ORCID: 0000-0001-8401-0545

Maintainer: Wancen Mu <wancen at live.unc.edu>

Citation (from within R, entercitation("airpart")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("airpart")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("airpart")
Differential allelic imbalance with airpartHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsATACSeq,CellBiology,ChIPSeq,Clustering,DifferentialExpression,FunctionalGenomics,GeneExpression,GeneRegulation,GraphAndNetwork,QualityControl,RNASeq,Regression,Sequencing,SingleCell,Software,Transcription,TranscriptomeVariant
Version1.18.0
In Bioconductor sinceBioC 3.13 (R-4.1) (4.5 years)
LicenseGPL-2
DependsR (>= 4.1)
ImportsSingleCellExperiment,SummarizedExperiment,S4Vectors,scater, stats,smurf,apeglm(>= 1.13.3),emdbook,mclust,clue,dynamicTreeCut,matrixStats,dplyr,plyr,ggplot2,ComplexHeatmap,forestplot,RColorBrewer,rlang,lpSolve, grid, grDevices, graphics, utils,pbapply
System Requirements
URLhttps://github.com/Wancen/airpart
Bug Reportshttps://github.com/Wancen/airpart/issues
See More
Suggestsknitr,rmarkdown,roxygen2 (>= 6.0.0),testthat (>= 3.0.0),gplots,tidyr
Linking To
Enhances
Depends On Me
Imports Me
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Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source Packageairpart_1.18.0.tar.gz
Windows Binary (x86_64) airpart_1.18.0.zip
macOS Binary (x86_64)airpart_1.18.0.tgz
macOS Binary (arm64)airpart_1.18.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/airpart
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/airpart
Bioc Package Browserhttps://code.bioconductor.org/browse/airpart/
Package Short Urlhttps://bioconductor.org/packages/airpart/
Package Downloads ReportDownload Stats

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