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TargetScore

This is thereleased version of TargetScore; for the devel version, seeTargetScore.

TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information

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DOI: 10.18129/B9.bioc.TargetScore


Bioconductor version: Release (3.22)

Infer the posterior distributions of microRNA targets by probabilistically modelling the likelihood microRNA-overexpression fold-changes and sequence-based scores. Variaitonal Bayesian Gaussian mixture model (VB-GMM) is applied to log fold-changes and sequence scores to obtain the posteriors of latent variable being the miRNA targets. The final targetScore is computed as the sigmoid-transformed fold-change weighted by the averaged posteriors of target components over all of the features.

Author: Yue Li

Maintainer: Yue Li <yueli at cs.toronto.edu>

Citation (from within R, entercitation("TargetScore")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("TargetScore")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("TargetScore")
TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence informationPDFR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsSoftware,miRNA
Version1.48.0
In Bioconductor sinceBioC 2.13 (R-3.0) (12 years)
LicenseGPL-2
Dependspracma,Matrix
Imports
System Requirements
URLhttp://www.cs.utoronto.ca/~yueli/software.html
See More
SuggestsTargetScoreData,gplots,Biobase,GEOquery
Linking To
Enhances
Depends On Me
Imports Me
Suggests MeTargetScoreData
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageTargetScore_1.48.0.tar.gz
Windows Binary (x86_64) TargetScore_1.48.0.zip
macOS Binary (x86_64)TargetScore_1.48.0.tgz
macOS Binary (arm64)TargetScore_1.48.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/TargetScore
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/TargetScore
Bioc Package Browserhttps://code.bioconductor.org/browse/TargetScore/
Package Short Urlhttps://bioconductor.org/packages/TargetScore/
Package Downloads ReportDownload Stats

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