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SPONGE

This is thereleased version of SPONGE; for the devel version, seeSPONGE.

Sparse Partial Correlations On Gene Expression

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DOI: 10.18129/B9.bioc.SPONGE


Bioconductor version: Release (3.21)

This package provides methods to efficiently detect competitive endogeneous RNA interactions between two genes. Such interactions are mediated by one or several miRNAs such that both gene and miRNA expression data for a larger number of samples is needed as input. The SPONGE package now also includes spongEffects: ceRNA modules offer patient-specific insights into the miRNA regulatory landscape.

Author: Markus List [aut, cre]ORCID iD ORCID: 0000-0002-0941-4168, Markus Hoffmann [aut]ORCID iD ORCID: 0000-0002-1920-288X, Lena Strasser [aut]ORCID iD ORCID: 0009-0007-7881-6818

Maintainer: Markus List <markus.list at tum.de>

Citation (from within R, entercitation("SPONGE")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("SPONGE")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SPONGE")
SPONGE vignetteHTMLR Script
spongEffects vignetteHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsGeneExpression,GeneRegulation,MachineLearning,NetworkInference,RandomForest,Regression,Software,SystemsBiology,Transcription,Transcriptomics
Version1.30.0
In Bioconductor sinceBioC 3.6 (R-3.4) (7.5 years)
LicenseGPL (>=3)
DependsR (>= 3.6)
ImportsBiobase, stats,ppcor,logging,foreach,doRNG,data.table,MASS,expm,gRbase,glmnet,igraph,iterators,tidyverse,caret,dplyr,biomaRt,randomForest,ggridges,cvms,ComplexHeatmap,ggplot2,MetBrewer,rlang,tnet,ggpubr,stringr,tidyr
System Requirements
URL
See More
Suggeststestthat,knitr,rmarkdown,visNetwork,ggrepel,gridExtra,digest,doParallel,bigmemory,GSVA
Linking To
Enhances
Depends On Me
Imports MemiRspongeR
Suggests MemirTarRnaSeq
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageSPONGE_1.30.0.tar.gz
Windows Binary (x86_64) SPONGE_1.30.0.zip
macOS Binary (x86_64)SPONGE_1.30.0.tgz
macOS Binary (arm64)SPONGE_1.30.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/SPONGE
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/SPONGE
Bioc Package Browserhttps://code.bioconductor.org/browse/SPONGE/
Package Short Urlhttps://bioconductor.org/packages/SPONGE/
Package Downloads ReportDownload Stats

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