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RVS

This is thereleased version of RVS; for the devel version, seeRVS.

Computes estimates of the probability of related individuals sharing a rare variant

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DOI: 10.18129/B9.bioc.RVS


Bioconductor version: Release (3.22)

Rare Variant Sharing (RVS) implements tests of association and linkage between rare genetic variant genotypes and a dichotomous phenotype, e.g. a disease status, in family samples. The tests are based on probabilities of rare variant sharing by relatives under the null hypothesis of absence of linkage and association between the rare variants and the phenotype and apply to single variants or multiple variants in a region (e.g. gene-based test).

Author: Alexandre Bureau, Ingo Ruczinski, Samuel Younkin, Thomas Sherman

Maintainer: Alexandre Bureau <alexandre.bureau at fmed.ulaval.ca>

Citation (from within R, entercitation("RVS")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("RVS")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("RVS")
The RVS PackageHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsExomeSeq,Genetics,GenomeWideAssociation,ImmunoOncology,Software,VariantDetection,WholeGenome
Version1.32.0
In Bioconductor sinceBioC 3.6 (R-3.4) (8 years)
LicenseGPL-2
DependsR (>= 3.5.0)
ImportsGENLIB,gRain,snpStats,kinship2, methods, stats, utils,R.utils
System Requirements
URL
See More
Suggestsknitr,testthat,rmarkdown,BiocStyle,VariantAnnotation
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageRVS_1.32.0.tar.gz
Windows Binary (x86_64) RVS_1.32.0.zip
macOS Binary (x86_64)RVS_1.32.0.tgz
macOS Binary (arm64)RVS_1.32.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/RVS
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/RVS
Bioc Package Browserhttps://code.bioconductor.org/browse/RVS/
Package Short Urlhttps://bioconductor.org/packages/RVS/
Package Downloads ReportDownload Stats

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