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RTN

This is thereleased version of RTN; for the devel version, seeRTN.

RTN: Reconstruction of Transcriptional regulatory Networks and analysis of regulons

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DOI: 10.18129/B9.bioc.RTN


Bioconductor version: Release (3.22)

A transcriptional regulatory network (TRN) consists of a collection of transcription factors (TFs) and the regulated target genes. TFs are regulators that recognize specific DNA sequences and guide the expression of the genome, either activating or repressing the expression the target genes. The set of genes controlled by the same TF forms a regulon. This package provides classes and methods for the reconstruction of TRNs and analysis of regulons.

Author: Clarice Groeneveld [ctb], Gordon Robertson [ctb], Xin Wang [aut], Michael Fletcher [aut], Florian Markowetz [aut], Kerstin Meyer [aut], and Mauro Castro [aut]

Maintainer: Mauro Castro <mauro.a.castro at gmail.com>

Citation (from within R, entercitation("RTN")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("RTN")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("RTN")
RTN: reconstruction of transcriptional regulatory networks and analysis of regulons."HTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsGeneExpression,GeneRegulation,GeneSetEnrichment,GeneticVariability,GraphAndNetwork,Network,NetworkEnrichment,NetworkInference,Software,Transcription
Version2.34.0
In Bioconductor sinceBioC 2.13 (R-3.0) (12 years)
LicenseArtistic-2.0
DependsR (>= 3.6.3), methods
ImportsRedeR,minet,viper,mixtools,snow, stats,limma,data.table,IRanges,igraph,S4Vectors,SummarizedExperiment,car,pwr,pheatmap, grDevices, graphics, utils
System Requirements
URLhttp://dx.doi.org/10.1038/ncomms3464
See More
SuggestsRUnit,BiocGenerics,BiocStyle,knitr,rmarkdown
Linking To
Enhances
Depends On MeRTNduals,RTNsurvival,Fletcher2013b
Imports Me
Suggests Megeneplast
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageRTN_2.34.0.tar.gz
Windows Binary (x86_64) RTN_2.34.0.zip
macOS Binary (x86_64)RTN_2.34.0.tgz
macOS Binary (arm64)RTN_2.34.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/RTN
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/RTN
Bioc Package Browserhttps://code.bioconductor.org/browse/RTN/
Package Short Urlhttps://bioconductor.org/packages/RTN/
Package Downloads ReportDownload Stats

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