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HiCDCPlus

This is thereleased version of HiCDCPlus; for the devel version, seeHiCDCPlus.

Hi-C Direct Caller Plus

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DOI: 10.18129/B9.bioc.HiCDCPlus


Bioconductor version: Release (3.22)

Systematic 3D interaction calls and differential analysis for Hi-C and HiChIP. The HiC-DC+ (Hi-C/HiChIP direct caller plus) package enables principled statistical analysis of Hi-C and HiChIP data sets – including calling significant interactions within a single experiment and performing differential analysis between conditions given replicate experiments – to facilitate global integrative studies. HiC-DC+ estimates significant interactions in a Hi-C or HiChIP experiment directly from the raw contact matrix for each chromosome up to a specified genomic distance, binned by uniform genomic intervals or restriction enzyme fragments, by training a background model to account for random polymer ligation and systematic sources of read count variation.

Author: Merve Sahin [cre, aut]ORCID iD ORCID: 0000-0003-3858-8332

Maintainer: Merve Sahin <merve.sahn at gmail.com>

Citation (from within R, entercitation("HiCDCPlus")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("HiCDCPlus")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("HiCDCPlus")
Analyzing Hi-C and HiChIP data with HiCDCPlusHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsDNA3DStructure,HiC,Normalization,Software
Version1.18.0
In Bioconductor sinceBioC 3.13 (R-4.1) (4.5 years)
LicenseGPL-3
Depends
ImportsRcpp,InteractionSet,GenomicInteractions,bbmle,pscl,BSgenome,data.table,dplyr,tidyr,GenomeInfoDb,rlang, splines,MASS,GenomicRanges,IRanges,tibble,R.utils,Biostrings,rtracklayer, methods,S4Vectors
System RequirementsJRE 8+
URL
See More
SuggestsBSgenome.Mmusculus.UCSC.mm9,BSgenome.Mmusculus.UCSC.mm10,BSgenome.Hsapiens.UCSC.hg19,BSgenome.Hsapiens.UCSC.hg38,RUnit,BiocGenerics,knitr,rmarkdown,HiTC,DESeq2,Matrix,BiocFileCache,rappdirs
Linking ToRcpp
Enhancesparallel
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageHiCDCPlus_1.18.0.tar.gz
Windows Binary (x86_64) HiCDCPlus_1.18.0.zip (64-bit only)
macOS Binary (x86_64)HiCDCPlus_1.18.0.tgz
macOS Binary (arm64)HiCDCPlus_1.18.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/HiCDCPlus
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/HiCDCPlus
Bioc Package Browserhttps://code.bioconductor.org/browse/HiCDCPlus/
Package Short Urlhttps://bioconductor.org/packages/HiCDCPlus/
Package Downloads ReportDownload Stats

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