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DeepTarget

This is thereleased version of DeepTarget; for the devel version, seeDeepTarget.

Deep characterization of cancer drugs

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DOI: 10.18129/B9.bioc.DeepTarget


Bioconductor version: Release (3.22)

This package predicts a drug’s primary target(s) or secondary target(s) by integrating large-scale genetic and drug screens from the Cancer Dependency Map project run by the Broad Institute. It further investigates whether the drug specifically targets the wild-type or mutated target forms. To show how to use this package in practice, we provided sample data along with step-by-step example.

Author: Sanju Sinha [aut], Trinh Nguyen [aut, cre]ORCID iD ORCID: 0000-0002-6606-6948, Ying Hu [aut]

Maintainer: Trinh Nguyen <tinh.nguyen at nih.gov>

Citation (from within R, entercitation("DeepTarget")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("DeepTarget")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DeepTarget")
Workflow Demonstration for Deep characterization of cancer drugsHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsCRISPR,DifferentialExpression,GeneExpression,GenePrediction,GeneSetEnrichment,GeneTarget,ImmunoOncology,Pathways,RNASeq,ReportWriting,Software
Version1.4.0
In Bioconductor sinceBioC 3.20 (R-4.4) (1 year)
LicenseGPL-2
DependsR (>= 4.2.0)
Importsfgsea,ggplot2,stringr,ggpubr,BiocParallel,pROC, stats, grDevices, graphics,depmap,readr,dplyr
System Requirements
URL
See More
SuggestsBiocStyle,knitr,rmarkdown
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageDeepTarget_1.4.0.tar.gz
Windows Binary (x86_64) DeepTarget_1.4.0.zip
macOS Binary (x86_64)DeepTarget_1.4.0.tgz
macOS Binary (arm64)DeepTarget_1.4.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/DeepTarget
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/DeepTarget
Bioc Package Browserhttps://code.bioconductor.org/browse/DeepTarget/
Package Short Urlhttps://bioconductor.org/packages/DeepTarget/
Package Downloads ReportDownload Stats

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