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Coralysis

This is thereleased version of Coralysis; for the devel version, seeCoralysis.

Coralysis sensitive identification of imbalanced cell types and states in single-cell data via multi-level integration

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DOI: 10.18129/B9.bioc.Coralysis


Bioconductor version: Release (3.22)

Coralysis is an R package featuring a multi-level integration algorithm for sensitive integration, reference-mapping, and cell-state identification in single-cell data. The multi-level integration algorithm is inspired by the process of assembling a puzzle - where one begins by grouping pieces based on low-to high-level features, such as color and shading, before looking into shape and patterns. This approach progressively blends the batch effects and separates cell types across multiple rounds of divisive clustering.

Author: António Sousa [cre, aut]ORCID iD ORCID: 0000-0003-4779-6459, Johannes Smolander [ctb, aut]ORCID iD ORCID: 0000-0003-3872-9668, Sini Junttila [aut]ORCID iD ORCID: 0000-0003-3754-5584, Laura L Elo [aut]ORCID iD ORCID: 0000-0001-5648-4532

Maintainer: António Sousa <aggode at utu.fi>

Citation (from within R, entercitation("Coralysis")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("Coralysis")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("Coralysis")
Cell StatesHTMLR Script
Get startedHTMLR Script
IntegrationHTMLR Script
Reference-mappingHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsAnnotation,BatchEffect,Classification,Clustering,DifferentialExpression,DimensionReduction,GeneExpression,Proteomics,RNASeq,SingleCell,Software,Transcriptomics
Version1.0.0
In Bioconductor sinceBioC 3.22 (R-4.5) (< 6 months)
LicenseGPL-3
DependsR (>= 4.2.0)
ImportsMatrix,aricode,LiblineaR,SparseM,ggplot2,umap,Rtsne,pheatmap,reshape2,dplyr,SingleCellExperiment,SummarizedExperiment,S4Vectors, methods, stats, utils,RANN,sparseMatrixStats,irlba,flexclust,scran,class,matrixStats,tidyr,cowplot,uwot,scatterpie,RColorBrewer,ggrastr,ggrepel,RSpectra,BiocParallel,withr
System Requirements
URLhttps://github.com/elolab/Coralysishttps://elolab.github.io/Coralysis/
Bug Reportshttps://github.com/elolab/Coralysis/issues
See More
Suggestsknitr,rmarkdown,bluster,ComplexHeatmap,circlize,scater,viridis,scRNAseq,SingleR,MouseGastrulationData,testthat (>= 3.0.0),BiocStyle,scrapper
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Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageCoralysis_1.0.0.tar.gz
Windows Binary (x86_64) Coralysis_1.0.0.zip
macOS Binary (x86_64)Coralysis_1.0.0.tgz
macOS Binary (arm64)Coralysis_1.0.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/Coralysis
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/Coralysis
Bioc Package Browserhttps://code.bioconductor.org/browse/Coralysis/
Package Short Urlhttps://bioconductor.org/packages/Coralysis/
Package Downloads ReportDownload Stats

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