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CellTrails

This is thereleased version of CellTrails; for the devel version, seeCellTrails.

Reconstruction, visualization and analysis of branching trajectories

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DOI: 10.18129/B9.bioc.CellTrails


Bioconductor version: Release (3.22)

CellTrails is an unsupervised algorithm for the de novo chronological ordering, visualization and analysis of single-cell expression data. CellTrails makes use of a geometrically motivated concept of lower-dimensional manifold learning, which exhibits a multitude of virtues that counteract intrinsic noise of single cell data caused by drop-outs, technical variance, and redundancy of predictive variables. CellTrails enables the reconstruction of branching trajectories and provides an intuitive graphical representation of expression patterns along all branches simultaneously. It allows the user to define and infer the expression dynamics of individual and multiple pathways towards distinct phenotypes.

Author: Daniel Ellwanger [aut, cre, cph]

Maintainer: Daniel Ellwanger <dc.ellwanger.dev at gmail.com>

Citation (from within R, entercitation("CellTrails")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("CellTrails")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CellTrails")
CellTrails: Reconstruction, visualization, and analysis of branching trajectories from single-cell expression dataPDFR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsClustering,DataRepresentation,DifferentialExpression,DimensionReduction,GeneExpression,ImmunoOncology,Sequencing,SingleCell,Software,TimeCourse
Version1.28.0
In Bioconductor sinceBioC 3.8 (R-3.5) (7 years)
LicenseArtistic-2.0
DependsR (>= 3.5),SingleCellExperiment
ImportsBiocGenerics,Biobase,cba,dendextend,dtw,EnvStats,ggplot2,ggrepel, grDevices,igraph,maptree, methods,mgcv,reshape2,Rtsne, stats, splines,SummarizedExperiment, utils
System Requirements
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SuggestsAnnotationDbi,destiny,RUnit,scater,scran,knitr,org.Mm.eg.db,rmarkdown
Linking To
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Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageCellTrails_1.28.0.tar.gz
Windows Binary (x86_64) CellTrails_1.28.0.zip
macOS Binary (x86_64)CellTrails_1.28.0.tgz
macOS Binary (arm64)CellTrails_1.28.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/CellTrails
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/CellTrails
Bioc Package Browserhttps://code.bioconductor.org/browse/CellTrails/
Package Short Urlhttps://bioconductor.org/packages/CellTrails/
Package Downloads ReportDownload Stats

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