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CTSV

This is thereleased version of CTSV; for the devel version, seeCTSV.

Identification of cell-type-specific spatially variable genes accounting for excess zeros

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DOI: 10.18129/B9.bioc.CTSV


Bioconductor version: Release (3.22)

The R package CTSV implements the CTSV approach developed by Jinge Yu and Xiangyu Luo that detects cell-type-specific spatially variable genes accounting for excess zeros. CTSV directly models sparse raw count data through a zero-inflated negative binomial regression model, incorporates cell-type proportions, and performs hypothesis testing based on R package pscl. The package outputs p-values and q-values for genes in each cell type, and CTSV is scalable to datasets with tens of thousands of genes measured on hundreds of spots. CTSV can be installed in Windows, Linux, and Mac OS.

Author: Jinge Yu Developer [aut, cre], Xiangyu Luo Developer [aut]

Maintainer: Jinge Yu Developer <yjgruc at ruc.edu.cn>

Citation (from within R, entercitation("CTSV")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("CTSV")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CTSV")
Basic UsageHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsGeneExpression,Genetics,Regression,Software,Spatial,StatisticalMethod
Version1.12.0
In Bioconductor sinceBioC 3.16 (R-4.2) (3 years)
LicenseGPL-3
DependsR (>= 4.2)
Importsstats,pscl,qvalue,BiocParallel, methods,knitr,SpatialExperiment,SummarizedExperiment
System Requirements
URLhttps://github.com/jingeyu/CTSV
Bug Reportshttps://github.com/jingeyu/CTSV/issues
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Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageCTSV_1.12.0.tar.gz
Windows Binary (x86_64) CTSV_1.12.0.zip
macOS Binary (x86_64)CTSV_1.12.0.tgz
macOS Binary (arm64)CTSV_1.12.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/CTSV
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/CTSV
Bioc Package Browserhttps://code.bioconductor.org/browse/CTSV/
Package Short Urlhttps://bioconductor.org/packages/CTSV/
Package Downloads ReportDownload Stats

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