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CONSTANd

This is thereleased version of CONSTANd; for the devel version, seeCONSTANd.

Data normalization by matrix raking

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DOI: 10.18129/B9.bioc.CONSTANd


Bioconductor version: Release (3.22)

Normalizes a data matrix `data` by raking (using the RAS method by Bacharach, see references) the Nrows by Ncols matrix such that the row means and column means equal 1. The result is a normalized data matrix `K=RAS`, a product of row mulipliers `R` and column multipliers `S` with the original matrix `A`. Missing information needs to be presented as `NA` values and not as zero values, because CONSTANd is able to ignore missing values when calculating the mean. Using CONSTANd normalization allows for the direct comparison of values between samples within the same and even across different CONSTANd-normalized data matrices.

Author: Joris Van Houtven [aut, trl], Geert Jan Bex [trl], Dirk Valkenborg [aut, cre]

Maintainer: Dirk Valkenborg <dirk.valkenborg at uhasselt.be>

Citation (from within R, entercitation("CONSTANd")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("CONSTANd")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CONSTANd")
CONSTANdHTMLR Script
Reference ManualPDF
NEWSText
LICENSEText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsCheminformatics,DifferentialExpression,Genetics,MassSpectrometry,Normalization,Preprocessing,Proteomics,Software,Transcriptomics
Version1.18.0
In Bioconductor sinceBioC 3.13 (R-4.1) (4.5 years)
LicensefileLICENSE
DependsR (>= 4.1)
Imports
System Requirements
URLqcquan.net/constand
Bug Reportshttps://github.com/PDiracDelta/CONSTANd/issues
See More
SuggestsBiocStyle,knitr,rmarkdown,tidyr,ggplot2,gridExtra,magick,Cairo,limma
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageCONSTANd_1.18.0.tar.gz
Windows Binary (x86_64) CONSTANd_1.18.0.zip
macOS Binary (x86_64)CONSTANd_1.18.0.tgz
macOS Binary (arm64)CONSTANd_1.18.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/CONSTANd
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/CONSTANd
Bioc Package Browserhttps://code.bioconductor.org/browse/CONSTANd/
Package Short Urlhttps://bioconductor.org/packages/CONSTANd/
Package Downloads ReportDownload Stats

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