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CIMICE

This is thereleased version of CIMICE; for the devel version, seeCIMICE.

CIMICE-R: (Markov) Chain Method to Inferr Cancer Evolution

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DOI: 10.18129/B9.bioc.CIMICE


Bioconductor version: Release (3.22)

CIMICE is a tool in the field of tumor phylogenetics and its goal is to build a Markov Chain (called Cancer Progression Markov Chain, CPMC) in order to model tumor subtypes evolution. The input of CIMICE is a Mutational Matrix, so a boolean matrix representing altered genes in a collection of samples. These samples are assumed to be obtained with single-cell DNA analysis techniques and the tool is specifically written to use the peculiarities of this data for the CMPC construction.

Author: Nicolò Rossi [aut, cre] (Lab. of Computational Biology and Bioinformatics, Department of Mathematics, Computer Science and Physics, University of Udine, ORCID:ORCID iD ORCID: 0000-0002-6353-7396)

Maintainer: Nicolò Rossi <olocin.issor at gmail.com>

Citation (from within R, entercitation("CIMICE")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("CIMICE")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CIMICE")
CIMICE-R: (Markov) Chain Method to Infer Cancer EvolutionHTMLR Script
Quick guideHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsBiologicalQuestion,GraphAndNetwork,NetworkInference,Phylogenetics,ResearchField,SingleCell,Software,StatisticalMethod,Technology
Version1.18.0
In Bioconductor sinceBioC 3.13 (R-4.1) (4.5 years)
LicenseArtistic-2.0
Depends
Importsdplyr,ggplot2,glue,tidyr,igraph,networkD3,visNetwork,ggcorrplot,purrr,ggraph, stats, utils,maftools,assertthat,tidygraph,expm,Matrix
System Requirements
URLhttps://github.com/redsnic/CIMICE
Bug Reportshttps://github.com/redsnic/CIMICE/issues
See More
SuggestsBiocStyle,knitr,rmarkdown,testthat,webshot
Linking To
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Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageCIMICE_1.18.0.tar.gz
Windows Binary (x86_64) CIMICE_1.18.0.zip
macOS Binary (x86_64)CIMICE_1.18.0.tgz
macOS Binary (arm64)CIMICE_1.18.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/CIMICE
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/CIMICE
Bioc Package Browserhttps://code.bioconductor.org/browse/CIMICE/
Package Short Urlhttps://bioconductor.org/packages/CIMICE/
Package Downloads ReportDownload Stats

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