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BioQC

This is thereleased version of BioQC; for the devel version, seeBioQC.

Detect tissue heterogeneity in expression profiles with gene sets

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DOI: 10.18129/B9.bioc.BioQC


Bioconductor version: Release (3.22)

BioQC performs quality control of high-throughput expression data based on tissue gene signatures. It can detect tissue heterogeneity in gene expression data. The core algorithm is a Wilcoxon-Mann-Whitney test that is optimised for high performance.

Author: Jitao David Zhang [cre, aut], Laura Badi [aut], Gregor Sturm [aut], Roland Ambs [aut], Iakov Davydov [aut]

Maintainer: Jitao David Zhang <jitao_david.zhang at roche.com>

Citation (from within R, entercitation("BioQC")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("BioQC")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("BioQC")
BioQC Algorithm: Speeding up the Wilcoxon-Mann-Whitney TestHTMLR Script
BioQC-benchmark: Testing Efficiency, Sensitivity and Specificity of BioQC on simulated and real-world dataHTMLR Script
BioQC-kidney: The kidney expression exampleHTMLR Script
BioQC: Detect tissue heterogeneity in gene expression dataHTMLR Script
Comparing the Wilcoxon-Mann-Whitney to alternative statistical testsHTMLR Script
Using BioQC with signed genesetsHTMLR Script
Reference ManualPDF
NEWSText
LICENSEText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsGeneExpression,GeneSetEnrichment,QualityControl,Software,StatisticalMethod
Version1.38.0
In Bioconductor sinceBioC 3.3 (R-3.3) (9.5 years)
LicenseGPL (>=3) + fileLICENSE
DependsR (>= 3.5.0),Biobase
ImportsedgeR,Rcpp, methods, stats, utils
System Requirements
URLhttps://accio.github.io/BioQC
Bug Reportshttps://accio.github.io/BioQC/issues
See More
Suggeststestthat,knitr,rmarkdown,lattice,latticeExtra,rbenchmark,gplots,gridExtra,org.Hs.eg.db,hgu133plus2.db,ggplot2,reshape2,plyr,ineq,covr,limma,RColorBrewer
Linking ToRcpp
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageBioQC_1.38.0.tar.gz
Windows Binary (x86_64) BioQC_1.38.0.zip
macOS Binary (x86_64)BioQC_1.38.0.tgz
macOS Binary (arm64)BioQC_1.38.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/BioQC
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/BioQC
Bioc Package Browserhttps://code.bioconductor.org/browse/BioQC/
Package Short Urlhttps://bioconductor.org/packages/BioQC/
Package Downloads ReportDownload Stats

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