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ATACseqTFEA

This is thereleased version of ATACseqTFEA; for the devel version, seeATACseqTFEA.

Transcription Factor Enrichment Analysis for ATAC-seq

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DOI: 10.18129/B9.bioc.ATACseqTFEA


Bioconductor version: Release (3.22)

Assay for Transpose-Accessible Chromatin using sequencing (ATAC-seq) is a technique to assess genome-wide chromatin accessibility by probing open chromatin with hyperactive mutant Tn5 Transposase that inserts sequencing adapters into open regions of the genome. ATACseqTFEA is an improvement of the current computational method that detects differential activity of transcription factors (TFs). ATACseqTFEA not only uses the difference of open region information, but also (or emphasizes) the difference of TFs footprints (cutting sites or insertion sites). ATACseqTFEA provides an easy, rigorous way to broadly assess TF activity changes between two conditions.

Author: Jianhong Ou [aut, cre]ORCID iD ORCID: 0000-0002-8652-2488

Maintainer: Jianhong Ou <jou at morgridge.org>

Citation (from within R, entercitation("ATACseqTFEA")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("ATACseqTFEA")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("ATACseqTFEA")
ATACseqTFEA VignetteHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsATACSeq,DNASeq,GeneRegulation,MNaseSeq,Sequencing,Software
Version1.12.0
In Bioconductor sinceBioC 3.16 (R-4.2) (3 years)
LicenseGPL-3
DependsR (>= 4.2)
ImportsBiocGenerics,S4Vectors,IRanges,Matrix,GenomicRanges,GenomicAlignments,Seqinfo,SummarizedExperiment,Rsamtools,motifmatchr,TFBSTools, stats,pracma,ggplot2,ggrepel,dplyr,limma, methods,rtracklayer
System Requirements
URLhttps://github.com/jianhong/ATACseqTFEA
Bug Reportshttps://github.com/jianhong/ATACseqTFEA/issues
See More
SuggestsBSgenome.Drerio.UCSC.danRer10,knitr,testthat,ATACseqQC,rmarkdown,BiocStyle
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageATACseqTFEA_1.12.0.tar.gz
Windows Binary (x86_64) ATACseqTFEA_1.12.0.zip (64-bit only)
macOS Binary (x86_64)ATACseqTFEA_1.12.0.tgz
macOS Binary (arm64)ATACseqTFEA_1.12.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/ATACseqTFEA
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/ATACseqTFEA
Bioc Package Browserhttps://code.bioconductor.org/browse/ATACseqTFEA/
Package Short Urlhttps://bioconductor.org/packages/ATACseqTFEA/
Package Downloads ReportDownload Stats

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