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ANCOMBC

This is thereleased version of ANCOMBC; for the devel version, seeANCOMBC.

Microbiome differential abudance and correlation analyses with bias correction

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DOI: 10.18129/B9.bioc.ANCOMBC


Bioconductor version: Release (3.22)

ANCOMBC is a package containing differential abundance (DA) and correlation analyses for microbiome data. Specifically, the package includes Analysis of Compositions of Microbiomes with Bias Correction 2 (ANCOM-BC2), Analysis of Compositions of Microbiomes with Bias Correction (ANCOM-BC), and Analysis of Composition of Microbiomes (ANCOM) for DA analysis, and Sparse Estimation of Correlations among Microbiomes (SECOM) for correlation analysis. Microbiome data are typically subject to two sources of biases: unequal sampling fractions (sample-specific biases) and differential sequencing efficiencies (taxon-specific biases). Methodologies included in the ANCOMBC package are designed to correct these biases and construct statistically consistent estimators.

Author: Huang Lin [cre, aut]ORCID iD ORCID: 0000-0002-4892-7871

Maintainer: Huang Lin <huanglinfrederick at gmail.com>

Citation (from within R, entercitation("ANCOMBC")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("ANCOMBC")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("ANCOMBC")
ANCOM TutorialHTMLR Script
ANCOM-BC TutorialHTMLR Script
ANCOM-BC2 TutorialHTMLR Script
SECOM TutorialHTMLR Script
Tutorial on Data Sanity and Integrity ChecksHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsDifferentialExpression,Microbiome,Normalization,Sequencing,Software
Version2.12.0
In Bioconductor sinceBioC 3.12 (R-4.0) (5 years)
LicenseArtistic-2.0
DependsR (>= 4.5.0)
Importsstats,CVXR,DescTools,Hmisc,MASS,Matrix,Rdpack,doParallel,doRNG,energy,foreach,gtools,lme4,lmerTest,multcomp,nloptr, parallel, utils
System Requirements
URLhttps://github.com/FrederickHuangLin/ANCOMBC
Bug Reportshttps://github.com/FrederickHuangLin/ANCOMBC/issues
See More
Suggestsmia(>= 1.6.0),DT,S4Vectors,SingleCellExperiment,SummarizedExperiment,TreeSummarizedExperiment,dplyr,knitr,magrittr,microbiome,phyloseq,rmarkdown,testthat,tidyr,tidyverse
Linking To
Enhances
Depends On Me
Imports Me
Suggests Medar,MiscMetabar
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageANCOMBC_2.12.0.tar.gz
Windows Binary (x86_64) ANCOMBC_2.12.0.zip
macOS Binary (x86_64)ANCOMBC_2.12.0.tgz
macOS Binary (arm64)ANCOMBC_2.12.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/ANCOMBC
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/ANCOMBC
Bioc Package Browserhttps://code.bioconductor.org/browse/ANCOMBC/
Package Short Urlhttps://bioconductor.org/packages/ANCOMBC/
Package Downloads ReportDownload Stats

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