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vulcan

This is thereleased version of vulcan; for the devel version, seevulcan.

VirtUaL ChIP-Seq data Analysis using Networks

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DOI: 10.18129/B9.bioc.vulcan


Bioconductor version: Release (3.22)

Vulcan (VirtUaL ChIP-Seq Analysis through Networks) is a package that interrogates gene regulatory networks to infer cofactors significantly enriched in a differential binding signature coming from ChIP-Seq data. In order to do so, our package combines strategies from different BioConductor packages: DESeq for data normalization, ChIPpeakAnno and DiffBind for annotation and definition of ChIP-Seq genomic peaks, csaw to define optimal peak width and viper for applying a regulatory network over a differential binding signature.

Author: Federico M. Giorgi, Andrew N. Holding, Florian Markowetz

Maintainer: Federico M. Giorgi <federico.giorgi at gmail.com>

Citation (from within R, entercitation("vulcan")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("vulcan")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("vulcan")
Vulcan: VirtUaL ChIP-Seq Analysis through NetworksPDFR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsChIPSeq,GeneExpression,NetworkEnrichment,Software,SystemsBiology
Version1.32.0
In Bioconductor sinceBioC 3.6 (R-3.4) (8 years)
LicenseLGPL-3
DependsR (>= 4.0),ChIPpeakAnno,TxDb.Hsapiens.UCSC.hg19.knownGene,zoo,GenomicRanges,S4Vectors,viper,DiffBind,locfit
Importswordcloud,csaw,gplots, stats, utils,caTools, graphics,DESeq2,Biobase
System Requirements
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Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source Packagevulcan_1.32.0.tar.gz
Windows Binary (x86_64) vulcan_1.32.0.zip (64-bit only)
macOS Binary (x86_64)vulcan_1.32.0.tgz
macOS Binary (arm64)vulcan_1.32.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/vulcan
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/vulcan
Bioc Package Browserhttps://code.bioconductor.org/browse/vulcan/
Package Short Urlhttps://bioconductor.org/packages/vulcan/
Package Downloads ReportDownload Stats

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