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UMI4Cats

This is thereleased version of UMI4Cats; for the devel version, seeUMI4Cats.

UMI4Cats: Processing, analysis and visualization of UMI-4C chromatin contact data

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DOI: 10.18129/B9.bioc.UMI4Cats


Bioconductor version: Release (3.22)

UMI-4C is a technique that allows characterization of 3D chromatin interactions with a bait of interest, taking advantage of a sonication step to produce unique molecular identifiers (UMIs) that help remove duplication bias, thus allowing a better differential comparsion of chromatin interactions between conditions. This package allows processing of UMI-4C data, starting from FastQ files provided by the sequencing facility. It provides two statistical methods for detecting differential contacts and includes a visualization function to plot integrated information from a UMI-4C assay.

Author: Mireia Ramos-Rodriguez [aut, cre]ORCID iD ORCID: 0000-0001-8083-2445, Marc Subirana-Granes [aut], Lorenzo Pasquali [aut]

Maintainer: Mireia Ramos-Rodriguez <mireiarr9 at gmail.com>

Citation (from within R, entercitation("UMI4Cats")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("UMI4Cats")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("UMI4Cats")
Analyzing UMI-4C data with UMI4CatsHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsAlignment,Coverage,Normalization,Preprocessing,QualityControl,Sequencing,Software,Visualization
Version1.20.0
In Bioconductor sinceBioC 3.12 (R-4.0) (5 years)
LicenseArtistic-2.0
DependsR (>= 4.1.0),SummarizedExperiment
Importsmagick,cowplot,scales,GenomicRanges,ShortRead,zoo,ggplot2,reshape2,regioneR,IRanges,S4Vectors,dplyr,BSgenome,Biostrings,DESeq2,R.utils,Rsamtools,stringr,Rbowtie2, methods,GenomeInfoDb,GenomicAlignments,RColorBrewer, utils, grDevices, stats,annotate,rlang,GenomicFeatures,BiocFileCache,rappdirs,fda,BiocGenerics
System Requirements
URLhttps://github.com/Pasquali-lab/UMI4Cats
Bug Reportshttps://github.com/Pasquali-lab/UMI4Cats/issues
See More
Suggestsknitr,rmarkdown,BiocStyle,org.Hs.eg.db,TxDb.Hsapiens.UCSC.hg19.knownGene,BSgenome.Hsapiens.UCSC.hg19,tidyr,testthat
Linking To
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Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageUMI4Cats_1.20.0.tar.gz
Windows Binary (x86_64) UMI4Cats_1.20.0.zip
macOS Binary (x86_64)UMI4Cats_1.20.0.tgz
macOS Binary (arm64)UMI4Cats_1.20.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/UMI4Cats
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/UMI4Cats
Bioc Package Browserhttps://code.bioconductor.org/browse/UMI4Cats/
Package Short Urlhttps://bioconductor.org/packages/UMI4Cats/
Package Downloads ReportDownload Stats

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