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SPIAT

This is thereleased version of SPIAT; for the devel version, seeSPIAT.

Spatial Image Analysis of Tissues

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DOI: 10.18129/B9.bioc.SPIAT


Bioconductor version: Release (3.22)

SPIAT (**Sp**atial **I**mage **A**nalysis of **T**issues) is an R package with a suite of data processing, quality control, visualization and data analysis tools. SPIAT is compatible with data generated from single-cell spatial proteomics platforms (e.g. OPAL, CODEX, MIBI, cellprofiler). SPIAT reads spatial data in the form of X and Y coordinates of cells, marker intensities and cell phenotypes. SPIAT includes six analysis modules that allow visualization, calculation of cell colocalization, categorization of the immune microenvironment relative to tumor areas, analysis of cellular neighborhoods, and the quantification of spatial heterogeneity, providing a comprehensive toolkit for spatial data analysis.

Author: Anna Trigos [aut]ORCID iD ORCID: 0000-0002-5915-2952, Yuzhou Feng [aut, cre]ORCID iD ORCID: 0000-0002-2955-4053, Tianpei Yang [aut], Mabel Li [aut], John Zhu [aut], Volkan Ozcoban [aut], Maria Doyle [aut]

Maintainer: Yuzhou Feng <yuzhou0610 at gmail.com>

Citation (from within R, entercitation("SPIAT")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("SPIAT")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SPIAT")
Basic analyses with SPIATHTMLR Script
Characterising tissue structure with SPIATHTMLR Script
Identifying cellular neighborhood with SPIATHTMLR Script
Overview of the SPIAT packageHTMLR Script
Quality control and visualisation with SPIATHTMLR Script
Quantifying cell colocalisation with SPIATHTMLR Script
Reading in data and data formatting in SPIATHTMLR Script
Spatial heterogeneity with SPIATHTMLR Script
Reference ManualPDF
NEWSText
LICENSEText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsBiomedicalInformatics,CellBiology,Clustering,DataImport,ImmunoOncology,QualityControl,SingleCell,Software,Spatial,Visualization
Version1.12.0
In Bioconductor sinceBioC 3.16 (R-4.2) (3 years)
LicenseArtistic-2.0 + fileLICENSE
DependsR (>= 4.2.0),SpatialExperiment(>= 1.8.0)
Importsapcluster (>= 1.4.7),ggplot2 (>= 3.2.1),gridExtra (>= 2.3),gtools (>= 3.8.1),reshape2 (>= 1.4.3),dplyr (>= 0.8.3),RANN (>= 2.6.1),pracma (>= 2.2.5),dbscan (>= 1.1-5),mmand (>= 1.5.4),tibble (>= 2.1.3), grDevices, stats, utils,vroom,dittoSeq,spatstat.geom, methods,spatstat.explore,raster,sp,SummarizedExperiment,rlang
System Requirements
URLhttps://trigosteam.github.io/SPIAT/
Bug Reportshttps://github.com/trigosteam/SPIAT/issues
See More
SuggestsBiocStyle,plotly (>= 4.9.0),knitr,rmarkdown,pkgdown,testthat, graphics,alphahull,Rtsne,umap,ComplexHeatmap,elsa
Linking To
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Depends On Me
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Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageSPIAT_1.12.0.tar.gz
Windows Binary (x86_64) SPIAT_1.12.0.zip
macOS Binary (x86_64)SPIAT_1.12.0.tgz
macOS Binary (arm64)SPIAT_1.12.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/SPIAT
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/SPIAT
Bioc Package Browserhttps://code.bioconductor.org/browse/SPIAT/
Package Short Urlhttps://bioconductor.org/packages/SPIAT/
Package Downloads ReportDownload Stats

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