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MOFA2

This is thereleased version of MOFA2; for the devel version, seeMOFA2.

Multi-Omics Factor Analysis v2

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DOI: 10.18129/B9.bioc.MOFA2


Bioconductor version: Release (3.22)

The MOFA2 package contains a collection of tools for training and analysing multi-omic factor analysis (MOFA). MOFA is a probabilistic factor model that aims to identify principal axes of variation from data sets that can comprise multiple omic layers and/or groups of samples. Additional time or space information on the samples can be incorporated using the MEFISTO framework, which is part of MOFA2. Downstream analysis functions to inspect molecular features underlying each factor, vizualisation, imputation etc are available.

Author: Ricard Argelaguet [aut, cre]ORCID iD ORCID: 0000-0003-3199-3722, Damien Arnol [aut]ORCID iD ORCID: 0000-0003-2462-534X, Danila Bredikhin [aut]ORCID iD ORCID: 0000-0001-8089-6983, Britta Velten [aut]ORCID iD ORCID: 0000-0002-8397-3515

Maintainer: Ricard Argelaguet <ricard.argelaguet at gmail.com>

Citation (from within R, entercitation("MOFA2")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("MOFA2")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MOFA2")
Downstream analysis: OverviewHTMLR Script
MEFISTO on simulated data (temporal)HTMLR Script
MOFA2: How to train a model in RHTMLR Script
Reference ManualPDF
LICENSEText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsBayesian,DimensionReduction,Software,Visualization
Version1.20.0
In Bioconductor sinceBioC 3.12 (R-4.0) (5 years)
LicensefileLICENSE
DependsR (>= 4.0)
Importsrhdf5,dplyr,tidyr,reshape2,pheatmap,ggplot2, methods,RColorBrewer,cowplot,ggrepel,reticulate,HDF5Array, grDevices, stats,magrittr,forcats, utils,corrplot,DelayedArray,Rtsne,uwot,basilisk,stringi
System RequirementsPython (>=3), numpy, pandas, h5py, scipy, argparse, sklearn, mofapy2
URLhttps://biofam.github.io/MOFA2/index.html
Bug Reportshttps://github.com/bioFAM/MOFA2
See More
Suggestsknitr,testthat,Seurat,SeuratObject,ggpubr,foreach,psych,MultiAssayExperiment,SummarizedExperiment,SingleCellExperiment,ggrastr,mvtnorm,GGally,rmarkdown,data.table,tidyverse,BiocStyle,Matrix,markdown
Linking To
Enhances
Depends On Me
Imports MeRFLOMICS
Suggests MeHoloFoodR,SUMO
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageMOFA2_1.20.0.tar.gz
Windows Binary (x86_64) MOFA2_1.20.0.zip
macOS Binary (x86_64)MOFA2_1.20.0.tgz
macOS Binary (arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/MOFA2
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/MOFA2
Bioc Package Browserhttps://code.bioconductor.org/browse/MOFA2/
Package Short Urlhttps://bioconductor.org/packages/MOFA2/
Package Downloads ReportDownload Stats

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