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GBScleanR

This is thereleased version of GBScleanR; for the devel version, seeGBScleanR.

Error correction tool for noisy genotyping by sequencing (GBS) data

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DOI: 10.18129/B9.bioc.GBScleanR


Bioconductor version: Release (3.22)

GBScleanR is a package for quality check, filtering, and error correction of genotype data derived from next generation sequcener (NGS) based genotyping platforms. GBScleanR takes Variant Call Format (VCF) file as input. The main function of this package is `estGeno()` which estimates the true genotypes of samples from given read counts for genotype markers using a hidden Markov model with incorporating uneven observation ratio of allelic reads. This implementation gives robust genotype estimation even in noisy genotype data usually observed in Genotyping-By-Sequnencing (GBS) and similar methods, e.g. RADseq. The current implementation accepts genotype data of a diploid population at any generation of multi-parental cross, e.g. biparental F2 from inbred parents, biparental F2 from outbred parents, and 8-way recombinant inbred lines (8-way RILs) which can be refered to as MAGIC population.

Author: Tomoyuki Furuta [aut, cre]ORCID iD ORCID: 0000-0002-0869-6626

Maintainer: Tomoyuki Furuta <f.tomoyuki at okayama-u.ac.jp>

Citation (from within R, entercitation("GBScleanR")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("GBScleanR")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("GBScleanR")
BasicUsageOfGBScleanR.htmlHTMLR Script
Reference ManualPDF
NEWSText
LICENSEText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsGeneticVariability,Genetics,HiddenMarkovModel,QualityControl,SNP,Sequencing,Software
Version2.4.4
In Bioconductor sinceBioC 3.15 (R-4.2) (3.5 years)
LicenseGPL-3 + fileLICENSE
DependsSeqArray
Importsstats, utils, methods,ggplot2,tidyr,expm,Rcpp,RcppParallel,gdsfmt
System RequirementsGNU make, C++11
URLhttps://github.com/tomoyukif/GBScleanR
Bug Reportshttps://github.com/tomoyukif/GBScleanR/issues
See More
SuggestsBiocStyle,testthat (>= 3.0.0),knitr,rmarkdown
Linking ToRcpp,RcppParallel
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageGBScleanR_2.4.4.tar.gz
Windows Binary (x86_64) GBScleanR_2.3.2.zip (64-bit only)
macOS Binary (x86_64)GBScleanR_2.4.4.tgz
macOS Binary (arm64)GBScleanR_2.4.4.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/GBScleanR
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/GBScleanR
Bioc Package Browserhttps://code.bioconductor.org/browse/GBScleanR/
Package Short Urlhttps://bioconductor.org/packages/GBScleanR/
Package Downloads ReportDownload Stats
Old Source Packages for BioC 3.22Source Archive

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