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methyLImp2

This is thedevelopment version of methyLImp2; for the stable release version, seemethyLImp2.

Missing value estimation of DNA methylation data

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DOI: 10.18129/B9.bioc.methyLImp2


Bioconductor version: Development (3.23)

This package allows to estimate missing values in DNA methylation data. methyLImp method is based on linear regression since methylation levels show a high degree of inter-sample correlation. Implementation is parallelised over chromosomes since probes on different chromosomes are usually independent. Mini-batch approach to reduce the runtime in case of large number of samples is available.

Author: Pietro Di Lena [aut]ORCID iD ORCID: 0000-0002-1838-8918, Anna Plaksienko [aut, cre]ORCID iD ORCID: 0000-0001-9607-057X, Claudia Angelini [aut]ORCID iD ORCID: 0000-0001-8350-8464, Christine Nardini [aut]ORCID iD ORCID: 0000-0001-7601-321X

Maintainer: Anna Plaksienko <anna at plaxienko.com>

Citation (from within R, entercitation("methyLImp2")):

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")# The following initializes usage of Bioc develBiocManager::install(version='devel')BiocManager::install("methyLImp2")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("methyLImp2")
methyLImp2 vignetteHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsDNAMethylation,MethylationArray,Microarray,Regression,Software
Version1.7.1
In Bioconductor sinceBioC 3.19 (R-4.4) (1.5 years)
LicenseGPL-3
DependsR (>= 4.3.0),ChAMPdata
ImportsBiocParallel, parallel, stats, methods,corpcor,SummarizedExperiment, utils
System Requirements
URLhttps://github.com/annaplaksienko/methyLImp2
Bug Reportshttps://github.com/annaplaksienko/methyLImp2/issues
See More
SuggestsBiocStyle,knitr,rmarkdown,spelling,testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackagemethyLImp2_1.7.1.tar.gz
Windows Binary (x86_64) methyLImp2_1.7.1.zip
macOS Binary (x86_64)methyLImp2_1.7.1.tgz
macOS Binary (arm64)methyLImp2_1.7.1.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/methyLImp2
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/methyLImp2
Bioc Package Browserhttps://code.bioconductor.org/browse/methyLImp2/
Package Short Urlhttps://bioconductor.org/packages/methyLImp2/
Package Downloads ReportDownload Stats

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