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SpotSweeper

This is thedevelopment version of SpotSweeper; for the stable release version, seeSpotSweeper.

Spatially-aware quality control for spatial transcriptomics

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DOI: 10.18129/B9.bioc.SpotSweeper


Bioconductor version: Development (3.23)

Spatially-aware quality control (QC) software for both spot-level and artifact-level QC in spot-based spatial transcripomics, such as 10x Visium. These methods calculate local (nearest-neighbors) mean and variance of standard QC metrics (library size, unique genes, and mitochondrial percentage) to identify outliers spot and large technical artifacts.

Author: Michael Totty [aut, cre]ORCID iD ORCID: 0000-0002-9292-8556, Stephanie Hicks [aut]ORCID iD ORCID: 0000-0002-7858-0231, Boyi Guo [aut]ORCID iD ORCID: 0000-0003-2950-2349

Maintainer: Michael Totty <mictott at gmail.com>

Citation (from within R, entercitation("SpotSweeper")):

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")# The following initializes usage of Bioc develBiocManager::install(version='devel')BiocManager::install("SpotSweeper")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("SpotSweeper")
Getting Started with `SpotSweeper`HTMLR Script
Reference ManualPDF
NEWSText
LICENSEText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsGeneExpression,QualityControl,Software,Spatial,Transcriptomics
Version1.7.0
In Bioconductor sinceBioC 3.19 (R-4.4) (1.5 years)
LicenseMIT + fileLICENSE
DependsR (>= 4.4.0)
ImportsSpatialExperiment,SummarizedExperiment,BiocNeighbors,SingleCellExperiment, stats,escheR,MASS,ggplot2,spatialEco, grDevices,BiocParallel
System Requirements
URLhttps://github.com/MicTott/SpotSweeper
Bug Reportshttps://support.bioconductor.org/tag/SpotSweeper
See More
Suggestsknitr,BiocStyle,rmarkdown,scuttle,STexampleData,ggpubr,testthat (>= 3.0.0)
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageSpotSweeper_1.7.0.tar.gz
Windows Binary (x86_64) SpotSweeper_1.7.0.zip
macOS Binary (x86_64)SpotSweeper_1.7.0.tgz
macOS Binary (arm64)SpotSweeper_1.7.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/SpotSweeper
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/SpotSweeper
Bioc Package Browserhttps://code.bioconductor.org/browse/SpotSweeper/
Package Short Urlhttps://bioconductor.org/packages/SpotSweeper/
Package Downloads ReportDownload Stats

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