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regionalpcs

This is thedevelopment version of regionalpcs; for the stable release version, seeregionalpcs.

Summarizing Regional Methylation with Regional Principal Components Analysis

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DOI: 10.18129/B9.bioc.regionalpcs


Bioconductor version: Development (3.23)

Functions to summarize DNA methylation data using regional principal components. Regional principal components are computed using principal components analysis within genomic regions to summarize the variability in methylation levels across CpGs. The number of principal components is chosen using either the Marcenko-Pasteur or Gavish-Donoho method to identify relevant signal in the data.

Author: Tiffany Eulalio [aut, cre]ORCID iD ORCID: 0000-0002-7084-9646

Maintainer: Tiffany Eulalio <tyeulalio at gmail.com>

Citation (from within R, entercitation("regionalpcs")):

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")# The following initializes usage of Bioc develBiocManager::install(version='devel')BiocManager::install("regionalpcs")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

Reference ManualPDF

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsDNAMethylation,DifferentialMethylation,MethylationArray,Software,StatisticalMethod
Version1.9.0
In Bioconductor sinceBioC 3.18 (R-4.3) (2 years)
LicenseMIT + file LICENSE
DependsR (>= 4.3.0)
Importsdplyr,PCAtools,tibble,GenomicRanges
System Requirements
URLhttps://github.com/tyeulalio/regionalpcs
Bug Reportshttps://github.com/tyeulalio/regionalpcs/issues
See More
Suggestsknitr,rmarkdown,RMTstat,testthat (>= 3.0.0),BiocStyle,tidyr,minfiData,TxDb.Hsapiens.UCSC.hg19.knownGene,IRanges
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Package Archives

FollowInstallation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64) regionalpcs_1.9.0.zip (64-bit only)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/regionalpcs
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/regionalpcs
Package Short Urlhttps://bioconductor.org/packages/regionalpcs/
Package Downloads ReportDownload Stats

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