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STADyUM

This is thedevelopment version of STADyUM; for the stable release version, seeSTADyUM.

Statistical Transcriptome Analysis under a Dynamic Unified Model

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DOI: 10.18129/B9.bioc.STADyUM


Bioconductor version: Development (3.23)

STADyUM is a package with functionality for analyzing nascent RNA read counts to infer transcription rates. This includes utilities for processing experimental nascent RNA read counts as well as for simulating PRO-seq data. Rates such as initiation, pause release and landing pad occupancy are estimated from either synthetic or experimental data. There are also options for varying pause sites and including steric hindrance of initiation in the model.

Author: Yixin Zhao [aut]ORCID iD ORCID: 0000-0002-7856-2818, Lingjie Liu [aut]ORCID iD ORCID: 0000-0002-5765-1213, Rebecca Hassett [aut, cre]ORCID iD ORCID: 0000-0001-5133-9387

Maintainer: Rebecca Hassett <hassett at cshl.edu>

Citation (from within R, entercitation("STADyUM")):

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")# The following initializes usage of Bioc develBiocManager::install(version='devel')BiocManager::install("STADyUM")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("STADyUM")
STADyUM: Simulating and Analyzing Transcription DynamicsHTMLR Script
Reference ManualPDF
NEWSText
LICENSEText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsSequencing,Software,StatisticalMethod,Transcription,Transcriptomics
Version1.1.3
In Bioconductor sinceBioC 3.22 (R-4.5) (< 6 months)
LicenseMIT + fileLICENSE
DependsR (>= 4.5.0)
ImportsGenomicRanges,IRanges,S4Vectors, methods,tibble,dplyr,ggplot2,progress,GenomeInfoDb,Rcpp,data.table,purrr,rtracklayer,tidyr,rlang,MASS
System Requirements
URLhttps://github.com/rhassett-cshl/STADyUM
Bug Reportshttps://github.com/rhassett-cshl/STADyUM
See More
Suggeststestthat (>= 3.0.0),knitr,rmarkdown,devtools
Linking ToRcpp
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageSTADyUM_1.1.3.tar.gz
Windows Binary (x86_64) STADyUM_1.1.3.zip
macOS Binary (x86_64)
macOS Binary (arm64)STADyUM_1.1.3.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/STADyUM
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/STADyUM
Bioc Package Browserhttps://code.bioconductor.org/browse/STADyUM/
Package Short Urlhttps://bioconductor.org/packages/STADyUM/
Package Downloads ReportDownload Stats

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