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hermes

This is thedevelopment version of hermes; for the stable release version, seehermes.

Preprocessing, analyzing, and reporting of RNA-seq data

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DOI: 10.18129/B9.bioc.hermes


Bioconductor version: Development (3.23)

Provides classes and functions for quality control, filtering, normalization and differential expression analysis of pre-processed `RNA-seq` data. Data can be imported from `SummarizedExperiment` as well as `matrix` objects and can be annotated from `BioMart`. Filtering for genes without too low expression or containing required annotations, as well as filtering for samples with sufficient correlation to other samples or total number of reads is supported. The standard normalization methods including cpm, rpkm and tpm can be used, and 'DESeq2` as well as voom differential expression analyses are available.

Author: Daniel Sabanés Bové [aut, cre], Namrata Bhatia [aut], Stefanie Bienert [aut], Benoit Falquet [aut], Haocheng Li [aut], Jeff Luong [aut], Lyndsee Midori Zhang [aut], Alex Richardson [aut], Simona Rossomanno [aut], Tim Treis [aut], Mark Yan [aut], Naomi Chang [aut], Chendi Liao [aut], Carolyn Zhang [aut], Joseph N. Paulson [aut], F. Hoffmann-La Roche AG [cph, fnd]

Maintainer: Daniel Sabanés Bové <daniel.sabanes_bove at rconis.com>

Citation (from within R, entercitation("hermes")):

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")# The following initializes usage of Bioc develBiocManager::install(version='devel')BiocManager::install("hermes")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("hermes")
Introduction to `hermes`HTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsDifferentialExpression,Normalization,Preprocessing,QualityControl,RNASeq,Software
Version1.15.0
In Bioconductor sinceBioC 3.15 (R-4.2) (3.5 years)
LicenseApache License 2.0
Dependsggfortify, R (>= 4.1),SummarizedExperiment(>= 1.16)
Importsassertthat,Biobase,BiocGenerics,biomaRt,checkmate (>= 2.1),circlize,ComplexHeatmap,DESeq2,dplyr,edgeR,EnvStats,forcats (>= 1.0.0),GenomicRanges,ggplot2,ggrepel (>= 0.9),IRanges,limma,magrittr,matrixStats (>= 1.5.0), methods,MultiAssayExperiment,purrr,R6,Rdpack (>= 2.6.2),rlang,S4Vectors, stats,tidyr, utils
System Requirements
URLhttps://insightsengineering.github.io/hermes/
Bug Reportshttps://github.com/insightsengineering/hermes/issues
See More
SuggestsBiocStyle,DelayedArray,DT, grid,httr,knitr,rmarkdown,statmod,testthat (>= 3.2.2),vdiffr (>= 1.0.8)
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Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source Packagehermes_1.15.0.tar.gz
Windows Binary (x86_64) hermes_1.15.0.zip
macOS Binary (x86_64)
macOS Binary (arm64)hermes_1.15.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/hermes
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/hermes
Bioc Package Browserhttps://code.bioconductor.org/browse/hermes/
Package Short Urlhttps://bioconductor.org/packages/hermes/
Package Downloads ReportDownload Stats

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