Meet the New AMD Instinct™ MI350 Series GPUs
The AMD Instinct™ MI350 Series GPUs set a new standard for Generative AI and high performance computing (HPC) in data centers. Built on the new cutting-edge 4th Gen AMD CDNA™ architecture, these GPUs deliver exceptional efficiency and performance for training massive AI models, high-speed inference, and complex HPC workloads like scientific simulations, data processing, and computational modeling.
Leadership Performance at Any Scale
AMD Instinct™ accelerators enable leadership performance for the data center, at any scale—from single-server solutions up to the world’s largest, Exascale-class supercomputers.
They are uniquely well-suited to power even the most demanding AI and HPC workloads, offering exceptional compute performance, large memory density, high bandwidth memory, and support for specialized data formats.
Under the Hood
AMD Instinct GPUs are built on AMD CDNA™ architecture, which offers Matrix Core Technologies and support for a broad range of datatype capabilities—from the highly efficient MXFP4 and MXFP6 (including INT8, OCP-FP8 and FP16/BF16 sparsity support for AI), to the most demanding FP64 for HPC.
Portfolio
AMD Instinct MI350 Series GPUs
AMD Instinct MI300 Series GPUs
AMD Instinct MI200 Series
Cloud Access
Experience AMD Instinct GPUs in the Cloud
Support your AI, HPC, and software development needs with programs supported by leading cloud service providers.
Server Solutions
AMD Instinct GPU Partners and Server Solutions
AMD collaborates with leading Original Equipment Manufacturers (OEMs), and platform designers to offer a robust ecosystem of AMD Instinct GPU-powered solutions.
Powering the AI & HPC Software Ecosystem with AMD Instinct™ GPUs
At AMD, we believe that advancing AI and HPC requires deep collaboration. Our collaborators span the full spectrum of AI and HPC ecosystem—from model development and large-scale training, to simulation, scientific research, and real-time inference. Together, we power breakthroughs in fields ranging from artificial intelligence to computational fluid dynamics, weather modelling, and beyond.
Case Studies
MindWalk™ Accelerates AI Drug Discovery with AMD
MindWalk™ scales rapid discovery with AMD Instinct™ MI300X GPUs and AMD EPYC™ CPUs on Vultr cloud, running bigger models faster, reducing months to ho…
December 09, 2025
Bud Ecosystem pioneers innovative new Indic LLM with AMD
Bud Ecosystem achieves faster training for India’s first commercially usable open-source Indic LLM using 40% fewer GPUs on Azure with instances powere…
December 09, 2025
Chile’s NLHPC Supercharged Research Performance with AMD
The National Laboratory for HPC in Chile doubled its scientific research performance per watt with AMD EPYC™ CPUs and AMD Instinct™ GPUs.
May 07, 2025
KT Cloud expands AI power with AMD Instinct™ accelerators
KT Cloud deployed AMD Instinct™ MI250 accelerators for a scalable AI cloud service with superior performance and significant cost reductions.
June 06, 2023
