Embryological structure dividing the trachea from the oesophagus
Thetracheoesophageal septum is an embryological structure. It is formed from thetracheoesophageal folds orridges which fuse in the midline. It divides theoesophagus from thetrachea duringprenatal development . Developmental abnormalities can lead to atracheoesophageal fistula .
The tracheoesophageal septum is formed from the tracheoesophageal folds laterally (longitudinal ridges), which fuse in the midline.[ 2] [ 3] oesophagus from thetrachea .[ 4] gestation .[ 3] foregut tube : thelaryngotracheal tube ventrally andoesophagus dorsally.[ 5]
The tracheoesophageal septum divides theoesophagus from thetrachea duringprenatal development .[ 4]
Clinical significance [ edit ] Developmental abnormalities of the tracheoesophageal septum can lead to atracheoesophageal fistula .[ 6] mutations ofgenes involved in its development.[ 4] [ 7] [ 8] [ 9]
^ Respiratory System ^ Bax, Klaas (2010)."27 - Esophageal Atresia and Tracheoesophageal Malformations" .Ashcraft's Pediatric Surgery (5th ed.).Saunders . pp. 345– 361.doi :10.1016/B978-1-4160-6127-4.00027-6 .ISBN 978-1-4160-6127-4 ^a b Sylvester, Karl G.; Ghole, Saif; Albanese, Craig T. (2010)."22 - Congenital Bronchopulmonary Malformations" .Ashcraft's Pediatric Surgery (5th ed.).Saunders . pp. 279– 289.doi :10.1016/B978-1-4160-6127-4.00022-7 .ISBN 978-1-4160-6127-4 ^a b c Shojaie, Sharareh; Post, Martin (2017)."64 - Molecular Mechanisms of Lung Development and Lung Branching Morphogenesis" .Fetal and Neonatal Physiology . Vol. 1 (5th ed.).Elsevier . pp. 658– 666.doi :10.1016/B978-0-323-35214-7.00064-0 .ISBN 978-0-323-35214-7 ^ Development of the Digestive System Archived 2007-11-23 at theWayback Machine ^ "Esophageal Atresia and Tracheoesophageal Fistula - February 15, 1999 - American Academy of Family Physicians" . Archived fromthe original on 2011-06-06. Retrieved2007-11-11 .^ Kulungowski, Ann M. (2018)."89 - Tracheoesophageal Malformations" .Abernathy's Surgical Secrets (7th ed.).Elsevier . pp. 409– 411.doi :10.1016/B978-0-323-47873-1.00089-9 .ISBN 978-0-323-47873-1 ^ Gulati, Reema; Radhakrishnan, Kadakkal; Thomson, Mike A. (2011)."20 - Developmental Anatomy and Physiology of the Esophagus" .Pediatric Gastrointestinal and Liver Disease (4th ed.).Saunders . pp. 207– 220.doi :10.1016/B978-1-4377-0774-8.10020-X .ISBN 978-1-4377-0774-8 ^ Kumar, S.; Salib, R. (2006)."Upper Airway Obstruction" .Encyclopedia of Respiratory Medicine .Academic Press . pp. 375– 385.doi :10.1016/B0-12-370879-6/00415-4 .ISBN 978-0-12-370879-3
