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Threose

From Wikipedia, the free encyclopedia
Threose[1]
d-Threose
l-Threose
Names
IUPAC names
d-Threose
l-Threose[2]
Systematic IUPAC name
(2S,3R)-2,3,4-Trihydroxybutanal (d)
(2R,3S)-2,3,4-Trihydroxybutanal (l)
Other names
Threotetrose
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard100.002.199Edit this at Wikidata
UNII
  • InChI=1S/C4H8O4/c5-1-3(7)4(8)2-6/h1,3-4,6-8H,2H2/t3-,4-/m1/s1 checkY
    Key: YTBSYETUWUMLBZ-QWWZWVQMSA-N checkY
  • InChI=1/C4H8O4/c5-1-3(7)4(8)2-6/h1,3-4,6-8H,2H2/t3-,4-/m1/s1
    Key: YTBSYETUWUMLBZ-QWWZWVQMBY
  • (d): O=C[C@@H](O)[C@H](O)CO
  • (l): OC[C@H](O)[C@@H](O)C=O
Properties
C4H8O4
Molar mass120.104 g·mol−1
AppearanceSyrup
Very soluble
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Chemical compound

Threose is a four-carbonmonosaccharide withmolecular formula C4H8O4. It has a terminalaldehyde group, rather than aketone, in its linear chain and so is considered part of thealdose family of monosaccharides. The threose name can be used to refer to both thed- andl-stereoisomers and more generally to theracemic mixture (d/L-, equal partsD- andL-) as well as to the more generic threose structure (absolute stereochemistry unspecified).

The prefix "threo-" which derives from threose (and "erythro-" from a correspondingdiastereomererythrose) offer a useful way to describe general organic structures with adjacent chiral centers, where "the prefixes... designate the relative configuration of the centers".[3] As is depicted in aFischer projection ofd-threose, the adjacent substituents will have asyn orientation in the isomer referred to as "threo", and areanti in the isomer referred to as "erythro".[3][4]

Fischer projections depicting the two enantiomers of threose

Although often inconsequential, threose in aqueous solution mainly exists as the hydrate owing to the following equilibrium:[5]

HOCH2CH(OH)CH(OH)CHO + H2O ⇌ HOCH2CH(OH)CH(OH)CH(OH)2

See also

[edit]

References

[edit]
  1. ^Merck Index, 11th Edition,9317
  2. ^"Carbohydrate Nomenclature".
  3. ^abFormulas Using Other Configurational Notations, W. Rausch, accessed 1 March 2011
  4. ^Prof. Rausch helpfully notes that the prefixes "may be applied to racemic compounds, as well as pure enantiomers and meso compounds", and that when depicted in the common "zig-zag" representation, adjacent "substituents may lie on the same side of the carbon chain... [syn] or on opposite sides... [anti]", which is opposite of their depiction in aFischer projection.
  5. ^Angyal, SJ; Wheen, RG (1980). "The Composition of Reducing Sugars in Aqueous Solution : Glyceraldehyde, Erythrose, Threose".Australian Journal of Chemistry.33 (5): 1001.doi:10.1071/CH9801001.
General
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