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Secondary palate

From Wikipedia, the free encyclopedia
Secondary palate
A sagittal section of apig's (Sus sp.) snout showing the secondary palate with pronouncedpalatine raphe.
Details
Identifiers
LatinPalatum secundarium,
palatum definitivum
TEpalate_by_E5.4.1.1.4.0.5 E5.4.1.1.4.0.5
Anatomical terminology

Thesecondary palate is an anatomical structure that divides thenasal cavity from theoral cavity in manyvertebrates.

In humanembryology, it refers to that portion of thehard palate that is formed by the growth of the two palatine shelves medially and their mutual fusion in the midline. It forms the majority of the adult palate and meets theprimary palate at theincisive foramen.

Clinical significance

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Secondary palate development begins in the sixth week ofpregnancy and can lead tocleft palate when development goes awry.

There are three major mechanisms known to cause this failure:

  1. Growth retardation — Palatal shelves do not grow enough to meet each other.
  2. Mechanical obstruction — Improper mouth size, or abnormal anatomical structures in the embryonic mouth prevent fully grown shelves from meeting each other.
  3. Midline epithelial dysfunction (MED)[1] - The surface mucosa of embryonic shelves is impaired, which causes a failure of palatal fusion.

Evolution

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The secondary palate is thought to have a significant role in the development of somewarm-blooded animals. The separation of the mouth from the nasal cavity also allowed chewing and breathing to occur at the same time. Early creatures with secondary palates includecrocodilians (who are cold-blooded), andcynodonts and a few others among thetherapsids, known from the fossil record in the mid-Permian.Mammals inherited our hard palates from the cynodonts.

References

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  1. ^Dudas, Marek; Li, Wai-Yee; Kim, Jieun; Yang, Alex; Kaartinen, Vesa (March 2007)."Palatal fusion – Where do the midline cells go?: A review on cleft palate, a major human birth defect".Acta Histochemica.109 (1):1–14.doi:10.1016/j.acthis.2006.05.009.PMID 16962647.
Development of thehead andneck
Face
Mouth
Palate
Tongue
General
Foregut
Midgut
Hindgut
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