Receptor (ligands) | GlyRTooltip Glycine receptor | - Positive modulators:Alcohols (e.g.,brometone,chlorobutanol (chloretone),ethanol (alcohol),tert-butanol (2M2P),tribromoethanol,trichloroethanol,trifluoroethanol)
- Alkylbenzene sulfonate
- Anandamide
- Barbiturates (e.g.,pentobarbital,sodium thiopental)
- Chlormethiazole
- D12-116
- Dihydropyridines (e.g.,nicardipine)
- Etomidate
- Ginseng constituents (e.g.,ginsenosides (e.g.,ginsenoside-Rf))
- Glutamic acid (glutamate)
- Ivermectin
- Ketamine
- Neuroactive steroids (e.g.,alfaxolone,pregnenolone (eltanolone),pregnenolone acetate,minaxolone,ORG-20599)
- Nitrous oxide
- Penicillin G
- Propofol
- Tamoxifen
- Tetrahydrocannabinol
- Triclofos
- Tropeines (e.g.,atropine,bemesetron,cocaine,LY-278584,tropisetron,zatosetron)
- Volatiles/gases (e.g.,chloral hydrate,chloroform,desflurane,diethyl ether (ether),enflurane,halothane,isoflurane,methoxyflurane,sevoflurane,toluene,trichloroethane (methyl chloroform),trichloroethylene)
- Xenon
- Zinc
- Antagonists:2-Aminostrychnine
- 2-Nitrostrychnine
- 4-Phenyl-4-formyl-N-methylpiperidine
- αEMBTL
- Bicuculline
- Brucine
- Cacotheline
- Caffeine
- Colchicine
- Colubrine
- Cyanotriphenylborate
- Dendrobine
- Diaboline
- Endocannabinoids (e.g.,2-AG,anandamide (AEA))
- Gaboxadol (THIP)
- Gelsemine
- iso-THAZ
- Isobutyric acid
- Isonipecotic acid
- Isostrychnine
- Laudanosine
- N-Methylbicuculline
- N-Methylstrychnine
- N,N-Dimethylmuscimol
- Nipecotic acid
- Pitrazepin
- Pseudostrychnine
- Quinolines (e.g.,4-hydroxyquinoline,4-hydroxyquinoline-3-carboxylic acid,5,7-CIQA,7-CIQ,7-TFQ,7-TFQA)
- RU-5135
- Sinomenine
- Strychnine
- Thiocolchicoside
- Tutin
- Negative modulators:Amiloride
- Benzodiazepines (e.g.,bromazepam,clonazepam,diazepam,flunitrazepam,flurazepam)
- Corymine
- Cyanotriphenylborate
- Daidzein
- Dihydropyridines (e.g.,nicardipine,nifedipine,nitrendipine)
- Furosemide
- Genistein
- Ginkgo constituents (e.g.,bilobalide,ginkgolides (e.g.,ginkgolide A,ginkgolide B,ginkgolide C,ginkgolide J,ginkgolide M))
- Imipramine
- NBQX
- Neuroactive steroids (e.g.,3α-androsterone sulfate,3β-androsterone sulfate,deoxycorticosterone,DHEA sulfate,pregnenolone sulfate,progesterone)
- Opioids (e.g.,codeine,dextromethorphan,dextrorphan,levomethadone,levorphanol,morphine,oripavine,pethidine,thebaine)
- Picrotoxin (i.e.,picrotin andpicrotoxinin)
- PMBA
- Riluzole
- Tropeines (e.g.,bemesetron,LY-278584,tropisetron,zatosetron)
- Verapamil
- Zinc
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NMDARTooltip N-Methyl-D-aspartate receptor | |
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