 | |
| Names | |
|---|---|
| IUPAC name 7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChEMBL |
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| UNII | |
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| Properties | |
| C17H18ClNO | |
| Molar mass | 287.78 g/mol |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
SCH-23390, also known ashalobenzazepine, is a synthetic compound that acts as adopamineD1 receptorantagonist with either minimal or negligible effects on theD2 receptor.
In a 1990 study in rats SCH-23390 offered significant protection from death indextroamphetamine overdose, without providing protection from death bymethamphetamine overdose. The compound provided significant protection from cocaine overdose in rats only at the lowest dose tested in the measurement series. This suggested that dextroamphetamine and methamphetamine at high (lethal) doses have different mechanisms of toxicity in rats.[1]
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