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Rosmarinate synthase

From Wikipedia, the free encyclopedia
rosmarinate synthase
Identifiers
EC no.2.3.1.140
CAS no.117590-80-4
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IntEnzIntEnz view
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Inenzymology, arosmarinate synthase (EC2.3.1.140) is anenzyme thatcatalyzes thechemical reaction

caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate{\displaystyle \rightleftharpoons } CoA + rosmarinate

Thus, the twosubstrates of this enzyme arecaffeoyl-CoA and3-(3,4-dihydroxyphenyl)lactate, whereas its twoproducts areCoA androsmarinate.

This enzyme belongs to the family oftransferases, specifically thoseacyltransferases transferring groups other than aminoacyl groups. Thesystematic name of this enzyme class iscaffeoyl-CoA:3-(3,4-dihydroxyphenyl)lactate 2'-O-caffeoyl-transferase. Other names in common use includerosmarinic acid synthase,caffeoyl-coenzyme A:3,4-dihydroxyphenyllactic acid,caffeoyltransferase, and4-coumaroyl-CoA:4-hydroxyphenyllactic acid 4-coumaroyl transferase. This enzyme participates intyrosine metabolism.

References

[edit]
  • Petersen M, Alfermann AW (1988). "Two new enzymes of rosmarinic acid biosynthesis from cell cultures of Coleus blumei: hydroxyphenylpyruvate reductase and rosmarinic acid synthase".Z. Naturforsch. C: Biosci.43:501–504.
2.3.1: other than amino-acyl groups
2.3.2:Aminoacyltransferases
2.3.3: converted into alkyl on transfer
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