Thepermeases aremembrane transport proteins, a class of multipass transmembrane proteins that allow the diffusion of a specific molecule in or out of thecell in the direction of aconcentration gradient, a form offacilitated diffusion.[1]
The permease binding is the first step of translocation. LacY protein from Escherichia coli is an example of a permease.[2]
It was originally discovered in the 1930s by Joy Adames[citation needed]. It is a transporter protein that helps in various aspects of cellular life including DNA replication, translation of RNA, and diffusion.
A permease (porter) is a protein or protein complex that catalyzes a vectorial reaction, irrespective of whether or not it also catalyzes a chemical or electron transfer reaction that drives the vectorial process.
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