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Nucleus raphe obscurus

From Wikipedia, the free encyclopedia
Nucleus raphe obscurus
Section of the medulla oblongata at about the middle of the olive. (Raphe nuclei not labeled, but 'raphe' labeled at left.)
Details
Identifiers
Latinnucleus raphes obscurus
MeSHD065849
NeuroNames740
NeuroLex IDbirnlex_1369
TA98A14.1.04.319
TA26037
FMA72585
Anatomical terms of neuroanatomy

Thenucleus raphe obscurus is one of the medullary raphe nuclei. It is located caudal to thenucleus raphe magnus. The nucleus raphe obscurus projects to thecerebellar lobes VI and VII and to crus II along with thenucleus raphe pontis.[1]

The nucleus raphes obscurus has also been implicated in the modulation of thehypoglossal nerve. It has been observed that theablation of this nucleus causes a change in the firing pattern of thiscranial nerve.[2]

In addition, the nucleus raphe obscurus mediatesexpiration via the effect ofserotonin and depresses periodic synaptic potentials.[3] It has also been shown that this nucleus stimulates gastrointestinal motor function; microinjections of 5-HT into the nucleus raphe obscurus increase gastric movement.[4]

See also

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References

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  1. ^Brodal, A (1981).Neurological Anatomy in relation to Clinical Medication (3rd ed.). Oxford Press.ISBN 978-0195026948.
  2. ^Peever, JH; Necakov, A; Duffin, J (2001). "Nucleus raphé obscurus modulates hypoglossal output of neonatal rat in vitro transverse brain stem slices".Journal of Applied Physiology.90 (1):269–279.doi:10.1152/jappl.2001.90.1.269.PMID 11133919.
  3. ^Lalley, PM; Benacka, R; Bischoff, AM; Richter, DW (1997). "Nucleus raphe obscurus evokes 5-HT-1A receptor-mediated modulation of respiratory neurons".Brain Research.747 (1):156–159.doi:10.1016/S0006-8993(96)01233-4.PMID 9042541.
  4. ^Krowicki, ZK; Hornby, PJ (1993). "Serotonin microinjected into the nucleus raphe obscurus increases intragastric pressure in the rat via a vagally mediated pathway".Journal of Pharmacology and Experimental Therapeutics.265 (1):468–476.PMID 8097247.
Anatomy of themedulla
Grey matter
Cranial nuclei
afferent:
efferent:
Dorsal
Ventral
White matter
Dorsal
Ventral
Surface
Front
Back
Grey
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