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LHASA

From Wikipedia, the free encyclopedia
This article is about the program that aids in total synthesis. For the data compression program, seeLhasa (computing). For other uses, seeLhasa (disambiguation).

LHASA (Logic and Heuristics Applied to Synthetic Analysis) is acomputer program developed in 1971 by the research group ofElias James Corey at theHarvard University Department ofChemistry. The program usesartificial intelligence techniques to discover sequences of reactions which may be used tosynthesize a molecule.[1] This program was one of the first to use a graphical interface to input and display chemical structures.[2]

References

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  1. ^Corey, E. J.; Wipke, W. Todd; Cramer, Richard D.; Howe, W. Jeffrey (1972-01-01)."Computer-assisted synthetic analysis. Facile man-machine communication of chemical structure by interactive computer graphics".Journal of the American Chemical Society.94 (2):421–430.doi:10.1021/ja00757a020.ISSN 0002-7863.
  2. ^Wang, Zhuang; Zhang, Wenhan; Liu, Bo (2021-06-26)."Computational Analysis of Synthetic Planning: Past and Future".Chinese Journal of Chemistry.39 (11):3127–3143.doi:10.1002/cjoc.202100273.ISSN 1001-604X.


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