LHASA (Logic and Heuristics Applied to Synthetic Analysis) is acomputer program developed in 1971 by the research group ofElias James Corey at theHarvard University Department ofChemistry. The program usesartificial intelligence techniques to discover sequences of reactions which may be used tosynthesize a molecule.[1] This program was one of the first to use a graphical interface to input and display chemical structures.[2]