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Jonathan Clayden

From Wikipedia, the free encyclopedia
British organic chemist and professor at Bristol

Jonathan Paul Clayden
Born (1968-02-06)6 February 1968 (age 57)
Kampala, Uganda
NationalityBritish
AwardsRoyal Society of Chemistry's Merck Prize
Royal Society of Chemistry's Stereochemistry Prize
Royal Society of Chemistry'sCorday-Morgan Medal
Scientific career
InstitutionsUniversity of Bristol
University of Manchester
University of Cambridge
ThesisThe asymmetric epoxidation of allylic phosphine oxides: a stereocontrolled synthesis of allylic systems (1993)
Doctoral advisorStuart Warren
Websitewww.claydenchemistry.net

Jonathan Paul ClaydenCChem FRSC (born 6 February 1968) is a Professor oforganic chemistry at theUniversity of Bristol.

Education

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Whilst at secondary school, he represented the UK at theInternational Chemistry Olympiad in 1986, winning a bronze medal. In 1992 he obtained hisPhD[1] at theUniversity of Cambridge working withDr Stuart Warren onasymmetric synthesis usingphosphine oxide chemistry. He then carried out a postdoc withProf Marc Julia and in 1994 became a lecturer inorganic chemistry at theUniversity of Manchester where he became a reader in 2000 and a Professor of Organic Chemistry in 2001. In 2015 he moved to a chair in chemistry at theUniversity of Bristol.

Research

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His research interests encompass various areas of synthesis and stereochemistry, particularly where conformation has a role to play: asymmetric synthesis, atropisomerism,[2] organolithium chemistry, remote stereochemical effects[3] and dynamic foldamer chemistry.[4] He is one of the authors of the organic chemistry textbook -Organic Chemistry by Clayden, Greeves, Warren and Wothers.[5] He also wroteOrganolithiums: Selectivity for Synthesis,[6] which concerns the use oforganolithium compounds in organic synthetic reactions.

From 2005 to 2011 he was editor-in-chief of the Open AccessBeilstein Journal of Organic Chemistry.

References

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  1. ^Clayden, Jonathan (1993).The asymmetric epoxidation of allylic phosphine oxides: a stereocontrolled synthesis of allylic systems (PhD thesis). University of Cambridge.
  2. ^Clayden, Jonathan; Moran, Wesley J.; Edwards, Paul J.; LaPlante, Steven R. (17 August 2009). "The Challenge of Atropisomerism in Drug Discovery".Angewandte Chemie International Edition.48 (35):6398–6401.doi:10.1002/anie.200901719.ISSN 1521-3773.PMID 19637174.
  3. ^Byrne, Liam; Solà, Jordi; Boddaert, Thomas; Marcelli, Tommaso; Adams, Ralph W.; Morris, Gareth A.; Clayden, Jonathan (3 January 2014)."Foldamer-Mediated Remote Stereocontrol: >1,60 Asymmetric Induction"(PDF).Angewandte Chemie International Edition.53 (1):151–155.doi:10.1002/anie.201308264.ISSN 1521-3773.PMID 24375739.
  4. ^Le Bailly, Bryden A. F.; Clayden, Jonathan (24 March 2016)."Dynamic foldamer chemistry".Chem. Commun.52 (27):4852–4863.doi:10.1039/c6cc00788k.hdl:1983/8e0ce263-cb79-455f-b99e-40f2db2b8ba5.PMID 26955864.
  5. ^Clayden, Jonathan; Greeves, Nick; Warren, Stuart (2012).Organic Chemistry (Second ed.). Oxford: OUP.ISBN 978-0-19-927029-3.
  6. ^Clayden, Jonathan (2002).Organolithiums: Selectivity for Synthesis. Oxford: Pergamon.ISBN 978-0-08-043261-8.
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